Cem Kuscu

Assistant Professor

  • 1185 Citations
  • 13 h-Index
20062019
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  • 2 Similar Profiles
Clustered Regularly Interspaced Short Palindromic Repeats Medicine & Life Sciences
Cell Movement Medicine & Life Sciences
Matrix Metalloproteinase 14 Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Genes Chemical Compounds
Chromatin Medicine & Life Sciences
Guide RNA Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences

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Research Output 2006 2019

  • 1185 Citations
  • 13 h-Index
  • 19 Article
  • 1 Chapter
  • 1 Comment/debate
  • 1 Short survey
1 Citation (Scopus)

Temporal and Spatial Epigenome Editing Allows Precise Gene Regulation in Mammalian Cells

Kuscu, C., Mammeadov, R., Czikora, A., Unlu, H., Tufan, T., Fischer, N. L., Arslan, S., Bekiranov, S., Kanemaki, M. & Adli, M., Jan 4 2019, In : Journal of Molecular Biology. 431, 1, p. 111-121 11 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Epigenomics
Gene Expression
Genes
Indoleacetic Acids
1 Citation (Scopus)

CRISPR knockout screening identifies combinatorial drug targets in pancreatic cancer and models cellular drug response

Szlachta, K., Kuscu, C., Tufan, T., Adair, S. J., Shang, S., Michaels, A. D., Mullen, M. G., Fischer, N. L., Yang, J., Liu, L., Trivedi, P., Stelow, E. B., Stukenberg, P. T., Parsons, J. T., Bauer, T. W. & Adli, M., Dec 1 2018, In : Nature Communications. 9, 1, 4275.

Research output: Contribution to journalArticle

Open Access
Clustered Regularly Interspaced Short Palindromic Repeats
Pancreatic Neoplasms
Screening
drugs
screening
2 Citations (Scopus)

Recurrent mutations at estrogen receptor binding sites alter chromatin topology and distal gene expression in breast cancer

Yang, J., Wei, X., Tufan, T., Kuscu, C., Unlu, H., Farooq, S., Demirtas, E., Paschal, B. M. & Adli, M., Nov 7 2018, In : Genome biology. 19, 1, 190.

Research output: Contribution to journalArticle

Open Access
Estrogen Receptors
breast neoplasms
topology
Chromatin
gene expression

Corrigendum to: “Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers” [EBioMedicine 8 (2016) 117–131](S235239641630175X)(10.1016/j.ebiom.2016.04.032)

Illendula, A., Gilmour, J., Grembecka, J., Tirumala, V. S. S., Boulton, A., Kuntimaddi, A., Schmidt, C., Wang, L., Pulikkan, J. A., Zong, H., Parlak, M., Kuscu, C., Pickin, A., Zhou, Y., Gao, Y., Mishra, L., Adli, M., Castilla, L. H., Rajewski, R. A., Janes, K. A. & 3 others, Guzman, M. L., Bonifer, C. & Bushweller, J. H., Nov 1 2017, In : EBioMedicine. 25, 1 p.

Research output: Contribution to journalComment/debate

Open Access
Transcription Factors
Molecules
Neoplasms
corrigendum
pyridine
67 Citations (Scopus)

CRISPR-STOP: Gene silencing through base-editing-induced nonsense mutations

Kuscu, C., Parlak, M., Tufan, T., Yang, J., Szlachta, K., Wei, X., Mammadov, R. & Adli, M., Jun 29 2017, In : Nature Methods. 14, 7, p. 710-712 3 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Nonsense Codon
Gene Silencing
Genes
Gene Knockout Techniques