• 1713 Citations
  • 16 h-Index
19952019
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Fingerprint Dive into the research topics where Kazuko Sakata is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 11 Similar Profiles
Brain-Derived Neurotrophic Factor Medicine & Life Sciences
Hippocampus Medicine & Life Sciences
Frontal Lobe Medicine & Life Sciences
Neurogenesis Medicine & Life Sciences
Brain Medicine & Life Sciences
Depression Medicine & Life Sciences
Proteins Medicine & Life Sciences
Long-Term Potentiation Medicine & Life Sciences

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Research Output 1995 2019

  • 1713 Citations
  • 16 h-Index
  • 25 Article
  • 1 Chapter
  • 1 Comment/debate

Thioredoxin-Interacting Protein (TXNIP) Associated NLRP3 Inflammasome Activation in Human Alzheimer's Disease Brain

Li, L., Ismael, S., Nasoohi, S., Sakata, K., Liao, F-F., Mcdonald, M. & Ishrat, T., Jan 1 2019, In : Journal of Alzheimer's Disease. 68, 1, p. 255-265 11 p.

Research output: Contribution to journalArticle

Inflammasomes
Thioredoxins
Alzheimer Disease
Brain
Proteins

The effect of enriched environment across ages: A study of anhedonia and BDNF gene induction

Dong, B. E., Xue, Y. & Sakata, K., Nov 1 2018, In : Genes, Brain and Behavior. 17, 8, e12485.

Research output: Contribution to journalArticle

Anhedonia
Brain-Derived Neurotrophic Factor
Genes
Frontal Lobe
Sucrose
15 Citations (Scopus)

A CNS-permeable Hsp90 inhibitor rescues synaptic dysfunction and memory loss in APP-overexpressing Alzheimer's mouse model via an HSF1-mediated mechanism

Wang, B., Liu, Y., Huang, L., Chen, J., Li, J. J., Wang, R., Kim, E., Chen, Y., Justicia, C., Sakata, K., Chen, H., Planas, A., Ostrom, R. S., Li, W., Yang, G., Mcdonald, M., Chen, R., Heck, D. & Liao, F-F., Jul 1 2017, In : Molecular Psychiatry. 22, 7, p. 990-1001 12 p.

Research output: Contribution to journalArticle

Memory Disorders
Heat-Shock Response
Therapeutic Uses
Heat-Shock Proteins
Intraperitoneal Injections
8 Citations (Scopus)

Bidirectional interplay of HSF1 degradation and UPR activation promotes tau hyperphosphorylation

Kim, E., Sakata, K. & Liao, F-F., Jul 1 2017, In : PLoS genetics. 13, 7, e1006849.

Research output: Contribution to journalArticle

unfolded protein response
Unfolded Protein Response
heat shock
heat stress
Shock

Hsp90 inhibitor induces nuclear translocation of HSF1 predominantly in hippocampal CA1 region

Wang, B., Liu, Y., Huang, L., Chen, J., Li, J. J., Wang, R., Kim, E., Chen, Y., Justicia, C., Sakata, K., Chen, H., Planas, A., Ostrom, R. S., Li, W., Yang, G., Mcdonald, M., Chen, R., Heck, D. & Liao, F-F., Jul 1 2017, In : Molecular Psychiatry. 22, 7, 1 p.

Research output: Contribution to journalComment/debate