• 3869 Citations
  • 33 h-Index
19942019
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Research Output 1994 2019

Lentiviral-mediated knock-down of GD3 synthase protects against MPTP-induced motor deficits and neurodegeneration

Dhanushkodi, A., Xue, Y., Roguski, E. E., Ding, Y., Matta, S. G., Heck, D., Fan, G. H. & Mcdonald, M., Jan 23 2019, In : Neuroscience Letters. 692, p. 53-63 11 p.

Research output: Contribution to journalArticle

Hypokinesia
Motor Skills
Gangliosides
G(M1) Ganglioside
Felidae
1 Citations

In utero exposure to fine particulate matter results in an altered neuroimmune phenotype in adult mice

Kulas, J. A., Hettwer, J. V., Sohrabi, M., Melvin, J. E., Manocha, G. D., Puig, K. L., Gorr, M. W., Tanwar, V., Mcdonald, M., Wold, L. E. & Combs, C. K., Oct 1 2018, In : Environmental Pollution. 241, p. 279-288 10 p.

Research output: Contribution to journalArticle

Particulate Matter
Animals
Brain
Phenotype
Air Pollution
11 Citations

A CNS-permeable Hsp90 inhibitor rescues synaptic dysfunction and memory loss in APP-overexpressing Alzheimer's mouse model via an HSF1-mediated mechanism

Wang, B., Liu, Y., Huang, L., Chen, J., Li, J. J., Wang, R., Kim, E., Chen, Y., Justicia, C., Sakata, K., Chen, H., Planas, A., Ostrom, R. S., Li, W., Yang, G., Mcdonald, M., Chen, R., Heck, D. & Liao, F-F., Jul 1 2017, In : Molecular Psychiatry. 22, 7, p. 990-1001 12 p.

Research output: Contribution to journalArticle

Memory Disorders
Heat-Shock Response
Therapeutic Uses
Heat-Shock Proteins
Intraperitoneal Injections

Hsp90 inhibitor induces nuclear translocation of HSF1 predominantly in hippocampal CA1 region

Wang, B., Liu, Y., Huang, L., Chen, J., Li, J. J., Wang, R., Kim, E., Chen, Y., Justicia, C., Sakata, K., Chen, H., Planas, A., Ostrom, R. S., Li, W., Yang, G., Mcdonald, M., Chen, R., Heck, D. & Liao, F-F., Jul 1 2017, In : Molecular Psychiatry. 22, 7, 1 p.

Research output: Contribution to journalComment/debate

3 Citations

Targeted deletion of GD3 synthase protects against MPTP-induced neurodegeneration

Akkhawattanangkul, Y., Maiti, P., Xue, Y., Aryal, D., Wetsel, W. C., Hamilton, D., Fowler, S. C. & Mcdonald, M., Jun 1 2017, In : Genes, Brain and Behavior. 16, 5, p. 522-536 15 p.

Research output: Contribution to journalArticle

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Tyrosine 3-Monooxygenase
Corpus Striatum
Parkinsonian Disorders
Dopamine