• 4048 Citations
  • 34 h-Index
19942019
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Dive into the research topics where Michael P. Mcdonald is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
Transgenic Mice Medicine & Life Sciences
Alzheimer Disease Medicine & Life Sciences
Gangliosides Medicine & Life Sciences
Galanin Medicine & Life Sciences
Sandhoff Disease Medicine & Life Sciences
Amyloid Medicine & Life Sciences
Brain Medicine & Life Sciences
Anxiety Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1994 2019

Lentiviral-mediated knock-down of GD3 synthase protects against MPTP-induced motor deficits and neurodegeneration

Dhanushkodi, A., Xue, Y., Roguski, E. E., Ding, Y., Matta, S. G., Heck, D., Fan, G. H. & Mcdonald, M., Jan 23 2019, In : Neuroscience Letters. 692, p. 53-63 11 p.

Research output: Contribution to journalArticle

Hypokinesia
Motor Skills
Gangliosides
G(M1) Ganglioside
Felidae

Thioredoxin-Interacting Protein (TXNIP) Associated NLRP3 Inflammasome Activation in Human Alzheimer's Disease Brain

Li, L., Ismael, S., Nasoohi, S., Sakata, K., Liao, F-F., Mcdonald, M. & Ishrat, T., Jan 1 2019, In : Journal of Alzheimer's Disease. 68, 1, p. 255-265 11 p.

Research output: Contribution to journalArticle

Inflammasomes
Thioredoxins
Alzheimer Disease
Brain
Proteins
2 Citations (Scopus)

In utero exposure to fine particulate matter results in an altered neuroimmune phenotype in adult mice

Kulas, J. A., Hettwer, J. V., Sohrabi, M., Melvin, J. E., Manocha, G. D., Puig, K. L., Gorr, M. W., Tanwar, V., Mcdonald, M., Wold, L. E. & Combs, C. K., Oct 1 2018, In : Environmental Pollution. 241, p. 279-288 10 p.

Research output: Contribution to journalArticle

Particulate Matter
Animals
Brain
Phenotype
Air Pollution
15 Citations (Scopus)

A CNS-permeable Hsp90 inhibitor rescues synaptic dysfunction and memory loss in APP-overexpressing Alzheimer's mouse model via an HSF1-mediated mechanism

Wang, B., Liu, Y., Huang, L., Chen, J., Li, J. J., Wang, R., Kim, E., Chen, Y., Justicia, C., Sakata, K., Chen, H., Planas, A., Ostrom, R. S., Li, W., Yang, G., Mcdonald, M., Chen, R., Heck, D. & Liao, F-F., Jul 1 2017, In : Molecular Psychiatry. 22, 7, p. 990-1001 12 p.

Research output: Contribution to journalArticle

Memory Disorders
Heat-Shock Response
Therapeutic Uses
Heat-Shock Proteins
Intraperitoneal Injections

Hsp90 inhibitor induces nuclear translocation of HSF1 predominantly in hippocampal CA1 region

Wang, B., Liu, Y., Huang, L., Chen, J., Li, J. J., Wang, R., Kim, E., Chen, Y., Justicia, C., Sakata, K., Chen, H., Planas, A., Ostrom, R. S., Li, W., Yang, G., Mcdonald, M., Chen, R., Heck, D. & Liao, F-F., Jul 1 2017, In : Molecular Psychiatry. 22, 7, 1 p.

Research output: Contribution to journalComment/debate