• 5163 Citations
  • 38 h-Index
19982019
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  • 2 Similar Profiles
Cholesterol Side-Chain Cleavage Enzyme Medicine & Life Sciences
Tubulin Modulators Medicine & Life Sciences
Melanoma Medicine & Life Sciences
Cholecalciferol Medicine & Life Sciences
Metabolism Chemical Compounds
Cells Chemical Compounds
Tubulin Medicine & Life Sciences
Neoplasms Medicine & Life Sciences

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Research Output 1998 2019

Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-4

Mangoni, A. A., Guillou, C., Eynde, J. J. V., Hulme, C., Jampilek, J., Li, W., Prokai-Tatrai, K., Rautio, J., Collina, S., Tuccinardi, T., Sousa, M. E., Sabatier, J. M., Galdiero, S., Karaman, R., Kokotos, G., Torri, G., Javier Luque, F., Helena Vasconcelos, M., Hadjipavlou-Litina, D., Siciliano, C. & 5 othersGütschow, M., Ragno, R., Gomes, P. A. C., Agrofoglio, L. A. & Muñoz-Torrero, D., Jan 1 2019, In : Molecules. p. 1-12 12 p.

Research output: Contribution to journalReview article

Pharmaceutical Chemistry
drugs
chemistry
Pharmaceutical Preparations
1 Citation (Scopus)

Current advances of tubulin inhibitors as dual acting small molecules for cancer therapy

Arnst, K. E., Banerjee, S., Chen, H., Deng, S., Hwang, D. J., Li, W. & Miller, D., Jan 1 2019, In : Medicinal Research Reviews.

Research output: Contribution to journalReview article

Tubulin Modulators
Microtubules
Pharmaceutical Preparations
Neoplasms
Therapeutics

Protective effects of novel derivatives of vitamin D 3 and lumisterol against UVB-induced damage in human keratinocytes involve activation of Nrf2 and p53 defense mechanisms

Chaiprasongsuk, A., Janjetovic, Z., Kim, T. K., Jarrett, S. G., D'Orazio, J. A., Holick, M. F., Tang, E. K. Y., Tuckey, R. C., Panich, U., Li, W. & Slominski, A. T., Jun 1 2019, In : Redox Biology. 24, 101206.

Research output: Contribution to journalArticle

Open Access
Ergosterol
Cholecalciferol
Keratinocytes
Chemical activation
Oxidants

Therapeutic efficacy of a novel βiII/βIV-tubulin inhibitor (VERU-111) in pancreatic cancer

Kashyap, V. K., Wang, Q., Setua, S., Nagesh, P. K. B., Chauhan, N., Kumari, S., Chowdhury, P., Miller, D., Yallapu, M., Li, W., Jaggi, M., Hafeez, B. & Chauhan, S., Jan 23 2019, In : Journal of Experimental and Clinical Cancer Research. 38, 1, 29.

Research output: Contribution to journalArticle

Tubulin Modulators
Pancreatic Neoplasms
Tubulin
Protein Isoforms
Neoplasms
14 Citations (Scopus)

A potent, metabolically stable tubulin inhibitor targets the colchicine binding site and overcomes taxane resistance

Arnst, K. E., Wang, Y., Hwang, D. J., Xue, Y., Costello, T., Hamilton, D., Chen, Q., Yang, J., Park, F., Dalton, J. T., Miller, D. & Li, W., Jan 1 2018, In : Cancer Research. 78, 1, p. 265-277 13 p.

Research output: Contribution to journalArticle

Tubulin Modulators
Colchicine
Binding Sites
Melanoma
Neoplasms