20-HETE in acute kidney injury

Richard J. Roman, Talha Akbulut, Frank Park, Kevin R. Regner

Research output: Contribution to journalComment/debate

10 Citations (Scopus)

Abstract

Ischemia/reperfusion injury (IRI) is a common cause of acute kidney injury (AKI) that is associated with a patient mortality of up to 50%. Currently there are not effective pharmacologic therapies for AKI. This Commentary highlights recent evidence indicating that 20-HETE plays an important role in IRI and that drugs that target this pathway have potential as therapeutic agents for AKI.

Original languageEnglish (US)
Pages (from-to)10-13
Number of pages4
JournalKidney International
Volume79
Issue number1
DOIs
StatePublished - Jan 1 2011

Fingerprint

Acute Kidney Injury
Reperfusion Injury
Mortality
Therapeutics
Pharmaceutical Preparations
20-hydroxy-5,8,11,14-eicosatetraenoic acid

All Science Journal Classification (ASJC) codes

  • Nephrology

Cite this

Roman, R. J., Akbulut, T., Park, F., & Regner, K. R. (2011). 20-HETE in acute kidney injury. Kidney International, 79(1), 10-13. https://doi.org/10.1038/ki.2010.396

20-HETE in acute kidney injury. / Roman, Richard J.; Akbulut, Talha; Park, Frank; Regner, Kevin R.

In: Kidney International, Vol. 79, No. 1, 01.01.2011, p. 10-13.

Research output: Contribution to journalComment/debate

Roman, RJ, Akbulut, T, Park, F & Regner, KR 2011, '20-HETE in acute kidney injury', Kidney International, vol. 79, no. 1, pp. 10-13. https://doi.org/10.1038/ki.2010.396
Roman, Richard J. ; Akbulut, Talha ; Park, Frank ; Regner, Kevin R. / 20-HETE in acute kidney injury. In: Kidney International. 2011 ; Vol. 79, No. 1. pp. 10-13.
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