A 9-year-old boy with chronic urticaria and progressive spondyloarthritis

Dai Park, Monica Brown, Peter Densen, Linda Myers, D. Betty Lew

Research output: Contribution to journalArticle

Abstract

A 9-year-old African American boy presented with chronic urticaria and progressive spondyloarthritis. Laboratory tests were abnormal for persistently positive antinuclear antibodies and undetectable total hemolytic complement (CH50) despite normal levels of complement C2, C3, and C4. Ultimately, further testing revealed an underlying deficiency in the immune system that may be associated with autoimmune disease and thus have a bearing on the patient's urticaria and spondyloarthritis. This is a unique presentation of a rare disease and underscores the importance of evaluating for systemic disease in the workup of chronic urticaria.

Original languageEnglish (US)
Pages (from-to)103-107
Number of pages5
JournalAllergy and Asthma Proceedings
Volume34
Issue number1
DOIs
StatePublished - Jan 1 2013

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Urticaria
Complement C2
Complement Hemolytic Activity Assay
Complement C4
Complement C3
Antinuclear Antibodies
Rare Diseases
African Americans
Autoimmune Diseases
Immune System

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Pulmonary and Respiratory Medicine

Cite this

A 9-year-old boy with chronic urticaria and progressive spondyloarthritis. / Park, Dai; Brown, Monica; Densen, Peter; Myers, Linda; Lew, D. Betty.

In: Allergy and Asthma Proceedings, Vol. 34, No. 1, 01.01.2013, p. 103-107.

Research output: Contribution to journalArticle

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