A clinical approach to the treatment of chronic hypernatremia

Ahmed Al-Absi, Elvira O. Gosmanova, Barry Wall

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Hypernatremia is a commonly encountered electrolyte disorder occurring in both the inpatient and outpatient settings. Community-acquired hypernatremia typically occurs at the extremes of age, whereas hospital-acquired hypernatremia affects patients of all age groups. Serum sodium concentration is linked to water homeostasis, which is dependent on the thirst mechanism, arginine vasopressin, and kidney function. Because both hypernatremia and the rate of correction of hypernatremia are associated with significant morbidity and mortality, prompt effective treatment is crucial. Chronic hypernatremia can be classified into 3 broad categories, hypovolemic, euvolemic, and hypervolemic forms, with each form having unique treatment considerations. In this teaching case, we provide a clinically based quantitative approach to the treatment of both hypervolemic and hypovolemic hypernatremia, which occurred in the same patient during the course of a prolonged illness.

Original languageEnglish (US)
Pages (from-to)1032-1038
Number of pages7
JournalAmerican Journal of Kidney Diseases
Volume60
Issue number6
DOIs
StatePublished - Dec 1 2012

Fingerprint

Hypernatremia
Hypovolemia
Therapeutics
Thirst
Arginine Vasopressin
Electrolytes
Inpatients
Teaching
Homeostasis
Outpatients
Age Groups
Sodium
Morbidity
Kidney
Mortality
Water
Serum

All Science Journal Classification (ASJC) codes

  • Nephrology

Cite this

A clinical approach to the treatment of chronic hypernatremia. / Al-Absi, Ahmed; Gosmanova, Elvira O.; Wall, Barry.

In: American Journal of Kidney Diseases, Vol. 60, No. 6, 01.12.2012, p. 1032-1038.

Research output: Contribution to journalArticle

Al-Absi, Ahmed ; Gosmanova, Elvira O. ; Wall, Barry. / A clinical approach to the treatment of chronic hypernatremia. In: American Journal of Kidney Diseases. 2012 ; Vol. 60, No. 6. pp. 1032-1038.
@article{3a889c9b9bc84ca59b10ebf0c8404d85,
title = "A clinical approach to the treatment of chronic hypernatremia",
abstract = "Hypernatremia is a commonly encountered electrolyte disorder occurring in both the inpatient and outpatient settings. Community-acquired hypernatremia typically occurs at the extremes of age, whereas hospital-acquired hypernatremia affects patients of all age groups. Serum sodium concentration is linked to water homeostasis, which is dependent on the thirst mechanism, arginine vasopressin, and kidney function. Because both hypernatremia and the rate of correction of hypernatremia are associated with significant morbidity and mortality, prompt effective treatment is crucial. Chronic hypernatremia can be classified into 3 broad categories, hypovolemic, euvolemic, and hypervolemic forms, with each form having unique treatment considerations. In this teaching case, we provide a clinically based quantitative approach to the treatment of both hypervolemic and hypovolemic hypernatremia, which occurred in the same patient during the course of a prolonged illness.",
author = "Ahmed Al-Absi and Gosmanova, {Elvira O.} and Barry Wall",
year = "2012",
month = "12",
day = "1",
doi = "10.1053/j.ajkd.2012.06.025",
language = "English (US)",
volume = "60",
pages = "1032--1038",
journal = "American Journal of Kidney Diseases",
issn = "0272-6386",
publisher = "W.B. Saunders Ltd",
number = "6",

}

TY - JOUR

T1 - A clinical approach to the treatment of chronic hypernatremia

AU - Al-Absi, Ahmed

AU - Gosmanova, Elvira O.

AU - Wall, Barry

PY - 2012/12/1

Y1 - 2012/12/1

N2 - Hypernatremia is a commonly encountered electrolyte disorder occurring in both the inpatient and outpatient settings. Community-acquired hypernatremia typically occurs at the extremes of age, whereas hospital-acquired hypernatremia affects patients of all age groups. Serum sodium concentration is linked to water homeostasis, which is dependent on the thirst mechanism, arginine vasopressin, and kidney function. Because both hypernatremia and the rate of correction of hypernatremia are associated with significant morbidity and mortality, prompt effective treatment is crucial. Chronic hypernatremia can be classified into 3 broad categories, hypovolemic, euvolemic, and hypervolemic forms, with each form having unique treatment considerations. In this teaching case, we provide a clinically based quantitative approach to the treatment of both hypervolemic and hypovolemic hypernatremia, which occurred in the same patient during the course of a prolonged illness.

AB - Hypernatremia is a commonly encountered electrolyte disorder occurring in both the inpatient and outpatient settings. Community-acquired hypernatremia typically occurs at the extremes of age, whereas hospital-acquired hypernatremia affects patients of all age groups. Serum sodium concentration is linked to water homeostasis, which is dependent on the thirst mechanism, arginine vasopressin, and kidney function. Because both hypernatremia and the rate of correction of hypernatremia are associated with significant morbidity and mortality, prompt effective treatment is crucial. Chronic hypernatremia can be classified into 3 broad categories, hypovolemic, euvolemic, and hypervolemic forms, with each form having unique treatment considerations. In this teaching case, we provide a clinically based quantitative approach to the treatment of both hypervolemic and hypovolemic hypernatremia, which occurred in the same patient during the course of a prolonged illness.

UR - http://www.scopus.com/inward/record.url?scp=84868701868&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84868701868&partnerID=8YFLogxK

U2 - 10.1053/j.ajkd.2012.06.025

DO - 10.1053/j.ajkd.2012.06.025

M3 - Article

VL - 60

SP - 1032

EP - 1038

JO - American Journal of Kidney Diseases

JF - American Journal of Kidney Diseases

SN - 0272-6386

IS - 6

ER -