A comparison of mezlocillin versus clindamycin/gentamicin for the treatment of postcesarean endomyometritis

Ronald D. Alvarez, Larry Kilgore, John F. Huddleston

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

In a prospective, randomized study of 96 patients after cesarean section who had endomyometritis, there was a therapeutic cure in 35 of 47 (74.5%) patients who received mezlocillin, in comparison with 42 of 49 (85.7%) patients who received clindamycin and gentamicin (p = 0.17). Only wound infections in the study population were predictive for therapeutic outcome. Four of the five patients who received mezlocillin and none of the three patients who received clindamycin and gentamicin with wound infections were associated with therapeutic failures. This suggests mezlocillin may not be as effective as clindamycin and gentamicin in successfully treating wound infections. The number of vaginal examinations in patients sectioned for cephalopelvic disproportion was associated with increased febrile morbidity, suggesting that an excessive number of vaginal examinations should be avoided in the laboring patient.

Original languageEnglish (US)
Pages (from-to)425-429
Number of pages5
JournalAmerican Journal of Obstetrics and Gynecology
Volume158
Issue number2
DOIs
StatePublished - Jan 1 1988

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Mezlocillin
Endometritis
Clindamycin
Gentamicins
Wound Infection
Gynecological Examination
Therapeutics
Cephalopelvic Disproportion
Cesarean Section
Fever
Prospective Studies
Morbidity

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynecology

Cite this

A comparison of mezlocillin versus clindamycin/gentamicin for the treatment of postcesarean endomyometritis. / Alvarez, Ronald D.; Kilgore, Larry; Huddleston, John F.

In: American Journal of Obstetrics and Gynecology, Vol. 158, No. 2, 01.01.1988, p. 425-429.

Research output: Contribution to journalArticle

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