A comparison of washed red blood cells versus packed red blood cells (AS-1) for cardiopulmonary bypass prime and their effects on blood glucose concentration in children

Michael Hosking, F. M. Beynen, H. S. Raimundo, W. C. Oliver, K. R. Williamson

Research output: Contribution to journalArticle

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Abstract

The effects on blood glucose concentrations of packed red blood cells (AS-1) (group I) versus washed red blood cells (group II) for cardiopulmonary bypass prime were compared in 20 infants weighing less than 10 kg undergoing cardiac surgical procedures. All patients were anesthetized with N2O/O2/isoflurane/fentanyl and received lactated Ringer's solution prior to bypass. Blood glucose concentrations prior to bypass were 85 ± 15 mg/dl (mean ± SD) in group I and 81 ± 14 mg/dl in group II. Blood glucose concentrations were 210 ± 21 mg/dl versus 78 ± 14 mg/dl (P < 0.001) 10 min after initiation of bypass, 241 ± 48 mg/dl versus 107 ± 28 mg/dl (P < 0.001) prior to separation from bypass, and 214 ± 52 mg/dl versus 97 ± 19 mg/dl (P < 0.001) after protamine administration in group I and group II, respectively. The use of washed red blood cells for cardiopulmonary bypass priming solution in infants significantly attenuates the increase in blood glucose concentration otherwise observed during cardiopulmonary bypass.

Original languageEnglish (US)
Pages (from-to)987-990
Number of pages4
JournalAnesthesiology
Volume72
Issue number6
DOIs
StatePublished - Jan 1 1990
Externally publishedYes

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Cardiopulmonary Bypass
Blood Glucose
Erythrocytes
Cardiac Surgical Procedures
Protamines
Isoflurane
Fentanyl
Blood Group Antigens

All Science Journal Classification (ASJC) codes

  • Anesthesiology and Pain Medicine

Cite this

A comparison of washed red blood cells versus packed red blood cells (AS-1) for cardiopulmonary bypass prime and their effects on blood glucose concentration in children. / Hosking, Michael; Beynen, F. M.; Raimundo, H. S.; Oliver, W. C.; Williamson, K. R.

In: Anesthesiology, Vol. 72, No. 6, 01.01.1990, p. 987-990.

Research output: Contribution to journalArticle

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