A critical analysis of renal blood flow distribution during hemorrhage in dogs

J. C. Passmore, Charles Leffler, R. E. Neiberger

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Renal blood flow (RBF) and its distribution were measured before and during hemorrhage by utilizing: 1) and electromagnetic flowmeter, 2) radioactive microspheres, 3) 85Kr washout and 4) a freeze-dissection 85Kr disappearance technique. Before hemorrhage, total RBF was 3.48 and 3.56 ml/gxmin measured with microspheres and flowmeter. Outer cortical flow was 6.65 and 7.56 ml/gxmin measured with microspheres and freeze-dissection respectively while inner cortical flow was 5.15 and 4.38 ml/gxmin. After hemorrhage, total flow as measured with either method was 2.3 ml/gxmin. Outer and inner cortical flow (3.85 and 3.08 ml/gxmin respectively) measured with microspheres was higher than that measured by freeze-dissection (1.54 and 1.60 ml/gxmin). The data suggest that preglomerular renal blood flow distribution may be different than cortical capillary flow distribution, especially during hemorrhage. The freeze-dissection technique provides flow rates for the outer medulla that are closest to component II (outer medullary flow) of any of the components of the externally monitored inert gas washout. Components I and II of the externally monitored washout may represent whole cortex and subcortical outer medulla respectively.

Original languageEnglish (US)
Pages (from-to)327-338
Number of pages12
JournalCirculatory Shock
Volume5
Issue number4
StatePublished - Dec 1 1978
Externally publishedYes

Fingerprint

Renal Circulation
Microspheres
Dissection
Dogs
Hemorrhage
Flowmeters
Noble Gases
Electromagnetic Phenomena

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

A critical analysis of renal blood flow distribution during hemorrhage in dogs. / Passmore, J. C.; Leffler, Charles; Neiberger, R. E.

In: Circulatory Shock, Vol. 5, No. 4, 01.12.1978, p. 327-338.

Research output: Contribution to journalArticle

Passmore, J. C. ; Leffler, Charles ; Neiberger, R. E. / A critical analysis of renal blood flow distribution during hemorrhage in dogs. In: Circulatory Shock. 1978 ; Vol. 5, No. 4. pp. 327-338.
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