A grading system for mesial temporal pathology (hippocampal sclerosis) from anterior temporal lobectomy

Allen R. Wyler, F Dohan, John B. Schweitzer, Allen D. Berry

Research output: Contribution to journalArticle

175 Citations (Scopus)

Abstract

A practical grading system based on routine light microscopic examination that quantifies histopathlogy of mesial temporal damage in temporal obectomy specimens is proposed. The aim of this grading system is to standardize the terminology used in reporting mesial temporal pathology that will help provide a means of comparing patient populations in research reports. This proposed system has five tiers that range from no hippocampal pathology present to Grade IV (marked hippocampal sclerosis) with three intermediate grades. Our internal blinded testing shows this grading system to be reliable and reproducible when used independently among individual pathologists.

Original languageEnglish (US)
Pages (from-to)220-225
Number of pages6
JournalJournal of Epilepsy
Volume5
Issue number4
DOIs
StatePublished - Jan 1 1992

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Anterior Temporal Lobectomy
Sclerosis
Pathology
Terminology
Light
Population

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Clinical Neurology

Cite this

A grading system for mesial temporal pathology (hippocampal sclerosis) from anterior temporal lobectomy. / Wyler, Allen R.; Dohan, F; Schweitzer, John B.; Berry, Allen D.

In: Journal of Epilepsy, Vol. 5, No. 4, 01.01.1992, p. 220-225.

Research output: Contribution to journalArticle

Wyler, Allen R. ; Dohan, F ; Schweitzer, John B. ; Berry, Allen D. / A grading system for mesial temporal pathology (hippocampal sclerosis) from anterior temporal lobectomy. In: Journal of Epilepsy. 1992 ; Vol. 5, No. 4. pp. 220-225.
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