A LANT6-like substance that is distinct from neuromedin N is present in pallidal and striatal neurons in monkeys

Research output: Contribution to journalArticle

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Abstract

The basal ganglia of rhesus and squirrel monkeys were examined using immunohistochemical techniques with antibodies against the neurotensin-related hexapeptides Lys8-Asn9-Neurotensin(8-13) (LANT6) and Neuromedin N. A high percentage of neurons in both segments of globus pallidus and many large neurons of the striatum were found to label for LANT6, but not Neuromedin N. Previous studies have shown that LANT6 or a LANT6-like substance is present in many pallidal neurons in a wide range of vertebrate species. The current results indicate that a LANT6-like substance that is distinct from Neuromedin N is also present in many pallidal neurons in primates. This raises the possibility that this substance may be involved in neurotransmission between the pallidum and its projection targets.

Original languageEnglish (US)
Pages (from-to)186-191
Number of pages6
JournalBrain Research
Volume422
Issue number1
DOIs
StatePublished - Sep 29 1987

Fingerprint

neuromedin N
Corpus Striatum
Haplorhini
Neurons
Globus Pallidus
neurotensin (8-13)
Saimiri
Basal Ganglia
Macaca mulatta
Synaptic Transmission
Primates
Vertebrates
Antibodies

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Molecular Biology
  • Developmental Biology
  • Clinical Neurology

Cite this

A LANT6-like substance that is distinct from neuromedin N is present in pallidal and striatal neurons in monkeys. / Reiner, Anton.

In: Brain Research, Vol. 422, No. 1, 29.09.1987, p. 186-191.

Research output: Contribution to journalArticle

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