A new and unexpected aminoisoquinoline formed under bischler‐napieralski reaction conditions provides for A new synthesis of 3‐aminoisoquinolines

Kimberly M. Markovich, Akihiko Hamada, Duane Miller

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Treatment of an amide, 1, of a substituted 2‐phenethylamine using Bischler‐Napieralski reaction conditions with acetonitrile as a solvent, gave the desired dihydroisoquinoline 2 as well as an unexpected 3‐aminoisoquinoline product 3. The applicability of this finding as a method of synthesizing 3‐aminoisoquinoline derivatives was examined.

Original languageEnglish (US)
Pages (from-to)1665-1667
Number of pages3
JournalJournal of Heterocyclic Chemistry
Volume27
Issue number6
DOIs
StatePublished - Jan 1 1990
Externally publishedYes

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Amides
Derivatives
G 1617
acetonitrile

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

Cite this

A new and unexpected aminoisoquinoline formed under bischler‐napieralski reaction conditions provides for A new synthesis of 3‐aminoisoquinolines. / Markovich, Kimberly M.; Hamada, Akihiko; Miller, Duane.

In: Journal of Heterocyclic Chemistry, Vol. 27, No. 6, 01.01.1990, p. 1665-1667.

Research output: Contribution to journalArticle

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