A new lignan with hypoglycemic activity from Tadehagi triquetrum

Jiani Wu, Cai Yun Zhang, Tingting Zhang, Dan Zhao, Ni An, Youbin Li, Nailiang Zhu, Shuai Wang, Feng Chen, Xiaopo Zhang

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A new lignan named tadehaginosin, together with a known compound 3,4-dihydro-4-(4′-hydroxyphenyl)-5,7-dihydroxycoumarin, was isolated from the aerial part of Tadehagi triquetrum. The new structure was determined by various spectroscopic techniques (1H and 13C APT, HSQC, HMBC, 1H-1HCOSY, NOESY and HR-ESI-MS). The two isolates were evaluated for their hypoglycemic effects in vitro. Biological investigation showed that both of them possessed the capability to increase glucose consumption by HepG2 cells.

Original languageEnglish (US)
Pages (from-to)1723-1727
Number of pages5
JournalNatural Product Research
Volume29
Issue number18
DOIs
StatePublished - Sep 17 2015

Fingerprint

Tadehagi
Lignans
glycemic effect
Hep G2 Cells
lignans
Hypoglycemic Agents
aerial parts
Antennas
Glucose
glucose
cells
methodology
electrospray ionization mass spectrometry
In Vitro Techniques
APT
tadehaginosin

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Plant Science
  • Organic Chemistry

Cite this

Wu, J., Zhang, C. Y., Zhang, T., Zhao, D., An, N., Li, Y., ... Zhang, X. (2015). A new lignan with hypoglycemic activity from Tadehagi triquetrum. Natural Product Research, 29(18), 1723-1727. https://doi.org/10.1080/14786419.2014.1003136

A new lignan with hypoglycemic activity from Tadehagi triquetrum. / Wu, Jiani; Zhang, Cai Yun; Zhang, Tingting; Zhao, Dan; An, Ni; Li, Youbin; Zhu, Nailiang; Wang, Shuai; Chen, Feng; Zhang, Xiaopo.

In: Natural Product Research, Vol. 29, No. 18, 17.09.2015, p. 1723-1727.

Research output: Contribution to journalArticle

Wu, J, Zhang, CY, Zhang, T, Zhao, D, An, N, Li, Y, Zhu, N, Wang, S, Chen, F & Zhang, X 2015, 'A new lignan with hypoglycemic activity from Tadehagi triquetrum', Natural Product Research, vol. 29, no. 18, pp. 1723-1727. https://doi.org/10.1080/14786419.2014.1003136
Wu, Jiani ; Zhang, Cai Yun ; Zhang, Tingting ; Zhao, Dan ; An, Ni ; Li, Youbin ; Zhu, Nailiang ; Wang, Shuai ; Chen, Feng ; Zhang, Xiaopo. / A new lignan with hypoglycemic activity from Tadehagi triquetrum. In: Natural Product Research. 2015 ; Vol. 29, No. 18. pp. 1723-1727.
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