A new view of prostaglandin E regulation of the immune response

Richard P. Phipps, Sidney Stein, Rachel L. Roper

Research output: Contribution to journalArticle

460 Citations (Scopus)

Abstract

Prostaglandins, particularly those o f the E series, are widely regarded as immunosuppressive products of eukaryotic cells that can downregulate many aspects of B- and T-cell function. In this article, Richard Phipps and colleagues present a different concept o f E series prostaglandins, based on recent evidence supporting a role for prostaglandins as potentiators of immunoglobulm class switching and o f the synthesis o f selected cytokines and cytokine receptors.

Original languageEnglish (US)
Pages (from-to)349-352
Number of pages4
JournalImmunology Today
Volume12
Issue number10
DOIs
StatePublished - Jan 1 1991

Fingerprint

Prostaglandins E
Prostaglandins
Immunoglobulin Class Switching
Cytokine Receptors
Eukaryotic Cells
Immunosuppressive Agents
Down-Regulation
Cytokines
T-Lymphocytes

All Science Journal Classification (ASJC) codes

  • Immunology

Cite this

A new view of prostaglandin E regulation of the immune response. / Phipps, Richard P.; Stein, Sidney; Roper, Rachel L.

In: Immunology Today, Vol. 12, No. 10, 01.01.1991, p. 349-352.

Research output: Contribution to journalArticle

Phipps, Richard P. ; Stein, Sidney ; Roper, Rachel L. / A new view of prostaglandin E regulation of the immune response. In: Immunology Today. 1991 ; Vol. 12, No. 10. pp. 349-352.
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