A novel preparation of methyl ketones through one-carbon homologation of aldehydes

Lei Wang, Pinhua Li, Jincan Yan, Zhongzhi Wu

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

A novel two-step aldehyde homologation procedure for the preparation of methyl ketones has been developed, which involves the use of 1,1-dibromo-1-alkenes as precursors and zinc metal as mediator in near-critical water.

Original languageEnglish (US)
Pages (from-to)4685-4688
Number of pages4
JournalTetrahedron Letters
Volume44
Issue number25
DOIs
StatePublished - Jun 16 2003

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Alkenes
Ketones
Aldehydes
Zinc
Carbon
Metals
Water

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

A novel preparation of methyl ketones through one-carbon homologation of aldehydes. / Wang, Lei; Li, Pinhua; Yan, Jincan; Wu, Zhongzhi.

In: Tetrahedron Letters, Vol. 44, No. 25, 16.06.2003, p. 4685-4688.

Research output: Contribution to journalArticle

Wang, Lei ; Li, Pinhua ; Yan, Jincan ; Wu, Zhongzhi. / A novel preparation of methyl ketones through one-carbon homologation of aldehydes. In: Tetrahedron Letters. 2003 ; Vol. 44, No. 25. pp. 4685-4688.
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