A Patient-Centric Goal in Time to Blood Pressure Control from Drug Therapy Initiation

Song Hee Hong, Junling Wang, Sunghee Tak

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A time frame in which newly diagnosed hypertensive patients attain blood pressure (BP) goal would guide patients through uncertainty associated with initiating drug therapy for hypertension control. This study estimates time to BP goal resulting from drug therapy initiation among real-world hypertensive patients and identifies factors associated with variations in time to BP goal. The study uses a historical cohort design. Hypertensive patients who had initiated antihypertensive drug therapy between July 1, 2002, and December 31, 2003, were followed up to 12 months until the end of 2004. Electronic medical records from a medical group were linked with pharmacy claims, as well as with medical claims. Survival analyses were used to compare lengths of time needed to reach BP goals. A total of 223 patients from a real world practice setting had initiated antihypertensive drug therapy. The patients took 3.25 months (95% CI: 2.49-4.82) to reach BP goal. The patient-centric time to BP goal was 7.1 weeks longer than those reported in controlled experimental settings. This finding highlights the gap between results of controlled clinical trials and their application to clinical practice, and informs healthcare practitioners of the importance of setting a patient-centric goal in pharmacological treatment of hypertension.

Original languageEnglish (US)
Pages (from-to)7-12
Number of pages6
JournalClinical and Translational Science
Volume6
Issue number1
DOIs
StatePublished - Feb 1 2013

Fingerprint

Drug therapy
Pressure control
Blood pressure
Blood Pressure
Drug Therapy
Antihypertensive Agents
Electronic medical equipment
Time and motion study
Hypertension
Electronic Health Records
Controlled Clinical Trials
Survival Analysis
Uncertainty
Pharmacology
Delivery of Health Care

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

A Patient-Centric Goal in Time to Blood Pressure Control from Drug Therapy Initiation. / Hong, Song Hee; Wang, Junling; Tak, Sunghee.

In: Clinical and Translational Science, Vol. 6, No. 1, 01.02.2013, p. 7-12.

Research output: Contribution to journalArticle

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