A pigmented dentigerous cyst in a patient with multiple dentigerous cysts of the jaws

A case report

Shokoufeh Shahrabi-Farahani, Mohammadtaghi Lotfalian

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Aim: The aim of this article is to report an unusual and interesting case of non-syndromic multiple dentigerous cysts of the maxilla and mandible associated with melanin pigment and melanocytes in the epithelial lining in one of the cysts. In addition, embryologic aspect and origin of melanocytes are briefly discussed. Background: Dentigerous cysts are the second most common odontogenic cysts after radicular cysts. They are usually solitary with multiple cysts reported on occasion in association with syndromes. While melanocytes and melanin-pigment are widely distributed in the skin, the nervous system, certain types of mucosa, uveal tract, and other areas, they are not normally present within bone in mammals. Report: A 37-year-old Iranian male was referred to an oral surgeon by his dentist for evaluation and treatment of multiple cyst-like radiolucent lesions around the crowns of some unerupted permanent teeth in both maxillary and mandibular anterior areas. The biopsy revealed numerous granules of melanin-pigment distributed throughout the epithelial lining of one of these cysts in addition to the characteristic histopathologic features of adentigerous cyst. Histochemical analysis confirmed the pigment was melanin, and many of the cells containing melanin were immunohistochemically positive for s-100 protein. Summary: Although the specific origin and pathologic significance of the melanocytes described here cannot be explained, it may be of interest for future investigations.

Original languageEnglish (US)
Pages (from-to)85-91
Number of pages7
JournalJournal of Contemporary Dental Practice
Volume8
Issue number5
StatePublished - Jul 1 2007

Fingerprint

Dentigerous Cyst
Melanins
Jaw
Melanocytes
Cysts
Unerupted Tooth
Radicular Cyst
Odontogenic Cysts
Maxilla
Dentists
Crowns
Mandible
Nervous System
Mammals
Mucous Membrane
Biopsy
Bone and Bones
Skin
Proteins

All Science Journal Classification (ASJC) codes

  • Dentistry(all)

Cite this

A pigmented dentigerous cyst in a patient with multiple dentigerous cysts of the jaws : A case report. / Shahrabi-Farahani, Shokoufeh; Lotfalian, Mohammadtaghi.

In: Journal of Contemporary Dental Practice, Vol. 8, No. 5, 01.07.2007, p. 85-91.

Research output: Contribution to journalArticle

@article{5c050e1b8ef042c59cf689ea0e43ad94,
title = "A pigmented dentigerous cyst in a patient with multiple dentigerous cysts of the jaws: A case report",
abstract = "Aim: The aim of this article is to report an unusual and interesting case of non-syndromic multiple dentigerous cysts of the maxilla and mandible associated with melanin pigment and melanocytes in the epithelial lining in one of the cysts. In addition, embryologic aspect and origin of melanocytes are briefly discussed. Background: Dentigerous cysts are the second most common odontogenic cysts after radicular cysts. They are usually solitary with multiple cysts reported on occasion in association with syndromes. While melanocytes and melanin-pigment are widely distributed in the skin, the nervous system, certain types of mucosa, uveal tract, and other areas, they are not normally present within bone in mammals. Report: A 37-year-old Iranian male was referred to an oral surgeon by his dentist for evaluation and treatment of multiple cyst-like radiolucent lesions around the crowns of some unerupted permanent teeth in both maxillary and mandibular anterior areas. The biopsy revealed numerous granules of melanin-pigment distributed throughout the epithelial lining of one of these cysts in addition to the characteristic histopathologic features of adentigerous cyst. Histochemical analysis confirmed the pigment was melanin, and many of the cells containing melanin were immunohistochemically positive for s-100 protein. Summary: Although the specific origin and pathologic significance of the melanocytes described here cannot be explained, it may be of interest for future investigations.",
author = "Shokoufeh Shahrabi-Farahani and Mohammadtaghi Lotfalian",
year = "2007",
month = "7",
day = "1",
language = "English (US)",
volume = "8",
pages = "85--91",
journal = "Journal of Contemporary Dental Practice",
issn = "1526-3711",
publisher = "Procter & Gamble Co.",
number = "5",

}

TY - JOUR

T1 - A pigmented dentigerous cyst in a patient with multiple dentigerous cysts of the jaws

T2 - A case report

AU - Shahrabi-Farahani, Shokoufeh

AU - Lotfalian, Mohammadtaghi

PY - 2007/7/1

Y1 - 2007/7/1

N2 - Aim: The aim of this article is to report an unusual and interesting case of non-syndromic multiple dentigerous cysts of the maxilla and mandible associated with melanin pigment and melanocytes in the epithelial lining in one of the cysts. In addition, embryologic aspect and origin of melanocytes are briefly discussed. Background: Dentigerous cysts are the second most common odontogenic cysts after radicular cysts. They are usually solitary with multiple cysts reported on occasion in association with syndromes. While melanocytes and melanin-pigment are widely distributed in the skin, the nervous system, certain types of mucosa, uveal tract, and other areas, they are not normally present within bone in mammals. Report: A 37-year-old Iranian male was referred to an oral surgeon by his dentist for evaluation and treatment of multiple cyst-like radiolucent lesions around the crowns of some unerupted permanent teeth in both maxillary and mandibular anterior areas. The biopsy revealed numerous granules of melanin-pigment distributed throughout the epithelial lining of one of these cysts in addition to the characteristic histopathologic features of adentigerous cyst. Histochemical analysis confirmed the pigment was melanin, and many of the cells containing melanin were immunohistochemically positive for s-100 protein. Summary: Although the specific origin and pathologic significance of the melanocytes described here cannot be explained, it may be of interest for future investigations.

AB - Aim: The aim of this article is to report an unusual and interesting case of non-syndromic multiple dentigerous cysts of the maxilla and mandible associated with melanin pigment and melanocytes in the epithelial lining in one of the cysts. In addition, embryologic aspect and origin of melanocytes are briefly discussed. Background: Dentigerous cysts are the second most common odontogenic cysts after radicular cysts. They are usually solitary with multiple cysts reported on occasion in association with syndromes. While melanocytes and melanin-pigment are widely distributed in the skin, the nervous system, certain types of mucosa, uveal tract, and other areas, they are not normally present within bone in mammals. Report: A 37-year-old Iranian male was referred to an oral surgeon by his dentist for evaluation and treatment of multiple cyst-like radiolucent lesions around the crowns of some unerupted permanent teeth in both maxillary and mandibular anterior areas. The biopsy revealed numerous granules of melanin-pigment distributed throughout the epithelial lining of one of these cysts in addition to the characteristic histopathologic features of adentigerous cyst. Histochemical analysis confirmed the pigment was melanin, and many of the cells containing melanin were immunohistochemically positive for s-100 protein. Summary: Although the specific origin and pathologic significance of the melanocytes described here cannot be explained, it may be of interest for future investigations.

UR - http://www.scopus.com/inward/record.url?scp=34347388446&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34347388446&partnerID=8YFLogxK

M3 - Article

VL - 8

SP - 85

EP - 91

JO - Journal of Contemporary Dental Practice

JF - Journal of Contemporary Dental Practice

SN - 1526-3711

IS - 5

ER -