A primer in cytokines

Ankush Gosain, Richard L. Gamelli

Research output: Contribution to journalReview article

40 Citations (Scopus)

Abstract

The host response to injury or infection is a complex interplay of endocrine, metabolic, and immunological alterations designed to promote wound healing and restore the system to a state of homeostasis. Cytokines are the primary mediators of the inflammatory response to injury. This article serves as an introduction to this important class of inflammatory mediators. The major pro- and anti-inflammatory cytokines as well as the chemokines are discussed. Results from laboratory and clinical attempts at manipulation of these mediators are discussed and recommendations for future research in anticytokine therapy are made.

Original languageEnglish (US)
Pages (from-to)7-12
Number of pages6
JournalJournal of Burn Care and Rehabilitation
Volume26
Issue number1
DOIs
StatePublished - Jan 2005
Externally publishedYes

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Cytokines
Wounds and Injuries
Chemokines
Wound Healing
Homeostasis
Anti-Inflammatory Agents
Infection
Therapeutics

All Science Journal Classification (ASJC) codes

  • Emergency Medicine
  • Rehabilitation
  • Surgery
  • Nursing(all)
  • Health Professions(all)

Cite this

A primer in cytokines. / Gosain, Ankush; Gamelli, Richard L.

In: Journal of Burn Care and Rehabilitation, Vol. 26, No. 1, 01.2005, p. 7-12.

Research output: Contribution to journalReview article

Gosain, Ankush ; Gamelli, Richard L. / A primer in cytokines. In: Journal of Burn Care and Rehabilitation. 2005 ; Vol. 26, No. 1. pp. 7-12.
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