A prospective study of familial aggregation of blood pressure in young children

Dawn K. Wilson, Lisa M. Klesges, Robert Klesges, Linda H. Eck, Catherine A. Hackett-Renner, Bruce S. Alpert, Edith T. Dalton

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

In a prospective study, we evaluated familial aggregation of blood pressure in a sample of 175 normotensive familes with children 3 to 6 yr old. Systolic and diastolic blood pressure measurements of parents and children were correlated at 1, 2, and 3 yr intervals. Spearman rank-order correlation coefficients between parents and children were significant for mother-son pairs. In particular, mother-son blood pressure correlation coefficients were significant for systolic blood pressure across all 3 yr and for diastolic blood pressure during yr 2. Further analyses were performed adjusting for body mass index (BMI), age, physical activity, sodium intake, potassium intake, and parental smoking status, and alcohol use. The Spearman correlation coefficients for mother-son pairs remained significant for yr 1 and 3 after adjusting for these blood pressure correlates. These results are consistent with cross-sectional studies and suggest that both genetic and environmental contributions to blood pressure status are important in young children.

Original languageEnglish (US)
Pages (from-to)959-969
Number of pages11
JournalJournal of Clinical Epidemiology
Volume45
Issue number9
DOIs
StatePublished - Jan 1 1992

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Prospective Studies
Blood Pressure
Nuclear Family
Mothers
Parents
Nonparametric Statistics
Potassium
Body Mass Index
Cross-Sectional Studies
Smoking
Sodium
Alcohols
Exercise

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Epidemiology
  • Public Health, Environmental and Occupational Health

Cite this

Wilson, D. K., Klesges, L. M., Klesges, R., Eck, L. H., Hackett-Renner, C. A., Alpert, B. S., & Dalton, E. T. (1992). A prospective study of familial aggregation of blood pressure in young children. Journal of Clinical Epidemiology, 45(9), 959-969. https://doi.org/10.1016/0895-4356(92)90112-Z

A prospective study of familial aggregation of blood pressure in young children. / Wilson, Dawn K.; Klesges, Lisa M.; Klesges, Robert; Eck, Linda H.; Hackett-Renner, Catherine A.; Alpert, Bruce S.; Dalton, Edith T.

In: Journal of Clinical Epidemiology, Vol. 45, No. 9, 01.01.1992, p. 959-969.

Research output: Contribution to journalArticle

Wilson, DK, Klesges, LM, Klesges, R, Eck, LH, Hackett-Renner, CA, Alpert, BS & Dalton, ET 1992, 'A prospective study of familial aggregation of blood pressure in young children', Journal of Clinical Epidemiology, vol. 45, no. 9, pp. 959-969. https://doi.org/10.1016/0895-4356(92)90112-Z
Wilson DK, Klesges LM, Klesges R, Eck LH, Hackett-Renner CA, Alpert BS et al. A prospective study of familial aggregation of blood pressure in young children. Journal of Clinical Epidemiology. 1992 Jan 1;45(9):959-969. https://doi.org/10.1016/0895-4356(92)90112-Z
Wilson, Dawn K. ; Klesges, Lisa M. ; Klesges, Robert ; Eck, Linda H. ; Hackett-Renner, Catherine A. ; Alpert, Bruce S. ; Dalton, Edith T. / A prospective study of familial aggregation of blood pressure in young children. In: Journal of Clinical Epidemiology. 1992 ; Vol. 45, No. 9. pp. 959-969.
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