A retrospective study of quality of life in a community sample of patients with early stage breast cancer

Mark S. Walker, Lee Schwartzberg, Edward J. Stepanski, Barry V. Fortner

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Few studies have examined the pattern of change in quality of life (QoL) over time among patients with breast cancer, or the impact of disease recurrence on QoL. This retrospective study examined QoL among patients with stage I-IIIB breast cancer. Individual, disease and treatment characteristics were abstracted from the medical record, and linked with QoL data collected as a routine part of patient care. The sample included patients with nonrecurrent (N = 100) and recurrent (N = 19) disease, who completed 1,449 QoL assessments. Linear mixed model analysis showed that disease recurrence significantly and adversely affected QoL across all domains. QoL did not appear to deteriorate before recurrence. The pattern of adjustment after recurrence varied across QoL domains in theoretically consistent ways. Study findings suggest that patients show improvement in some areas after recurrence, but generally do not recover previous levels of QoL.

Original languageEnglish (US)
Pages (from-to)415-422
Number of pages8
JournalBreast Cancer Research and Treatment
Volume115
Issue number2
DOIs
StatePublished - May 1 2009

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Retrospective Studies
Quality of Life
Breast Neoplasms
Recurrence
Medical Records
Linear Models
Patient Care

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

A retrospective study of quality of life in a community sample of patients with early stage breast cancer. / Walker, Mark S.; Schwartzberg, Lee; Stepanski, Edward J.; Fortner, Barry V.

In: Breast Cancer Research and Treatment, Vol. 115, No. 2, 01.05.2009, p. 415-422.

Research output: Contribution to journalArticle

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