A ribosomal protein gene cluster is encoded in the mitochondrial DNA of Dictyostelium discoideum

UGA termination codons and similarity of gene order to Acanthamoeba castellanii

Masao Iwamoto, Min Pi, Mika Kurihara, Takahiro Morio, Yoshimasa Tanaka

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

We sequenced a region of about 14.5 kb downstream from the ribosomal protein L11 gene (rpl11) in the mitochondrial DNA (54 ± 2 kb) of the cellular slime mold Dictyostelium discoideum. Sequence analysis revealed that eleven ribosomal protein genes and six open reading frames (ORFs) formed a cluster arranged in the order: rpl11-orf189-rps12-rps7-rpl2-rps19-orf425-orf1740-rpl16-rpl14-orf188-rps14-rps8 -rpl6-rps13-orf127-orf796. This order was very similar to that of homologous genes in Acanthamoeba castellanii mitochondrial DNA. The N-terminal region of ORF425 and the C-terminal region of ORF1740 had partial similarities to the S3 ribosomal protein of other organisms. The termination codons of rpl16 and orf188 were UGA, which has not hitherto been found in genes encoded in D. discoideum mitochondrial DNA.

Original languageEnglish (US)
Pages (from-to)304-310
Number of pages7
JournalCurrent Genetics
Volume33
Issue number4
DOIs
StatePublished - Apr 1 1998
Externally publishedYes

Fingerprint

Acanthamoeba castellanii
Dictyostelium
Gene Order
Terminator Codon
Multigene Family
Mitochondrial DNA
Genes
Dictyosteliida
Ribosomal Proteins
Open Reading Frames
Sequence Analysis
ribosomal protein L7-L12

All Science Journal Classification (ASJC) codes

  • Genetics

Cite this

A ribosomal protein gene cluster is encoded in the mitochondrial DNA of Dictyostelium discoideum : UGA termination codons and similarity of gene order to Acanthamoeba castellanii. / Iwamoto, Masao; Pi, Min; Kurihara, Mika; Morio, Takahiro; Tanaka, Yoshimasa.

In: Current Genetics, Vol. 33, No. 4, 01.04.1998, p. 304-310.

Research output: Contribution to journalArticle

@article{5cc31e5644b141e280792e3514136243,
title = "A ribosomal protein gene cluster is encoded in the mitochondrial DNA of Dictyostelium discoideum: UGA termination codons and similarity of gene order to Acanthamoeba castellanii",
abstract = "We sequenced a region of about 14.5 kb downstream from the ribosomal protein L11 gene (rpl11) in the mitochondrial DNA (54 ± 2 kb) of the cellular slime mold Dictyostelium discoideum. Sequence analysis revealed that eleven ribosomal protein genes and six open reading frames (ORFs) formed a cluster arranged in the order: rpl11-orf189-rps12-rps7-rpl2-rps19-orf425-orf1740-rpl16-rpl14-orf188-rps14-rps8 -rpl6-rps13-orf127-orf796. This order was very similar to that of homologous genes in Acanthamoeba castellanii mitochondrial DNA. The N-terminal region of ORF425 and the C-terminal region of ORF1740 had partial similarities to the S3 ribosomal protein of other organisms. The termination codons of rpl16 and orf188 were UGA, which has not hitherto been found in genes encoded in D. discoideum mitochondrial DNA.",
author = "Masao Iwamoto and Min Pi and Mika Kurihara and Takahiro Morio and Yoshimasa Tanaka",
year = "1998",
month = "4",
day = "1",
doi = "10.1007/s002940050341",
language = "English (US)",
volume = "33",
pages = "304--310",
journal = "Current Genetics",
issn = "0172-8083",
publisher = "Springer Verlag",
number = "4",

}

TY - JOUR

T1 - A ribosomal protein gene cluster is encoded in the mitochondrial DNA of Dictyostelium discoideum

T2 - UGA termination codons and similarity of gene order to Acanthamoeba castellanii

AU - Iwamoto, Masao

AU - Pi, Min

AU - Kurihara, Mika

AU - Morio, Takahiro

AU - Tanaka, Yoshimasa

PY - 1998/4/1

Y1 - 1998/4/1

N2 - We sequenced a region of about 14.5 kb downstream from the ribosomal protein L11 gene (rpl11) in the mitochondrial DNA (54 ± 2 kb) of the cellular slime mold Dictyostelium discoideum. Sequence analysis revealed that eleven ribosomal protein genes and six open reading frames (ORFs) formed a cluster arranged in the order: rpl11-orf189-rps12-rps7-rpl2-rps19-orf425-orf1740-rpl16-rpl14-orf188-rps14-rps8 -rpl6-rps13-orf127-orf796. This order was very similar to that of homologous genes in Acanthamoeba castellanii mitochondrial DNA. The N-terminal region of ORF425 and the C-terminal region of ORF1740 had partial similarities to the S3 ribosomal protein of other organisms. The termination codons of rpl16 and orf188 were UGA, which has not hitherto been found in genes encoded in D. discoideum mitochondrial DNA.

AB - We sequenced a region of about 14.5 kb downstream from the ribosomal protein L11 gene (rpl11) in the mitochondrial DNA (54 ± 2 kb) of the cellular slime mold Dictyostelium discoideum. Sequence analysis revealed that eleven ribosomal protein genes and six open reading frames (ORFs) formed a cluster arranged in the order: rpl11-orf189-rps12-rps7-rpl2-rps19-orf425-orf1740-rpl16-rpl14-orf188-rps14-rps8 -rpl6-rps13-orf127-orf796. This order was very similar to that of homologous genes in Acanthamoeba castellanii mitochondrial DNA. The N-terminal region of ORF425 and the C-terminal region of ORF1740 had partial similarities to the S3 ribosomal protein of other organisms. The termination codons of rpl16 and orf188 were UGA, which has not hitherto been found in genes encoded in D. discoideum mitochondrial DNA.

UR - http://www.scopus.com/inward/record.url?scp=0031944366&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031944366&partnerID=8YFLogxK

U2 - 10.1007/s002940050341

DO - 10.1007/s002940050341

M3 - Article

VL - 33

SP - 304

EP - 310

JO - Current Genetics

JF - Current Genetics

SN - 0172-8083

IS - 4

ER -