A targeted, image-guided and dually locked photoresponsive drug delivery system

S. Karthik, Prashanth Kumar Bhusetty Nagesh, Moumita Gangopadhyay, Mahitosh Mandal, N. D.Pradeep Singh

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

We have developed a new targeted image-guided photoresponsive drug delivery system (DDS) based on a dual locking strategy. Excitation of the DDS by fluorescent light results in the first unlocking and activation of the drug, and allows real-time monitoring of the prodrug. Extended irradiation results in a second unlocking, giving drug release within cancer cells.

Original languageEnglish (US)
Pages (from-to)728-732
Number of pages5
JournalJournal of Materials Chemistry B
Volume3
Issue number5
DOIs
StatePublished - Feb 7 2015

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Prodrugs
Pharmaceutical Preparations
Chemical activation
Cells
Irradiation
Monitoring
Drug Delivery Systems

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Biomedical Engineering
  • Materials Science(all)

Cite this

A targeted, image-guided and dually locked photoresponsive drug delivery system. / Karthik, S.; Bhusetty Nagesh, Prashanth Kumar; Gangopadhyay, Moumita; Mandal, Mahitosh; Singh, N. D.Pradeep.

In: Journal of Materials Chemistry B, Vol. 3, No. 5, 07.02.2015, p. 728-732.

Research output: Contribution to journalArticle

Karthik, S. ; Bhusetty Nagesh, Prashanth Kumar ; Gangopadhyay, Moumita ; Mandal, Mahitosh ; Singh, N. D.Pradeep. / A targeted, image-guided and dually locked photoresponsive drug delivery system. In: Journal of Materials Chemistry B. 2015 ; Vol. 3, No. 5. pp. 728-732.
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