A three-year follow-up on standard versus thin wall ePTFE grafts for hemodialysis

B. J. Lenz, H. C. Veldenz, J. W. Dennis, S. Khansarinia, L. R. Atteberry, Mitchell Goldman

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Purpose: Expanded polytetraflouroethylene (ePTFE) grafts are the most popular prosthetic grafts for hemodialysis patients in whom autogenous fistulas cannot be constructed. Long-term studies to study the durability and complication rate of the different wall configurations of ePTFE grafts have not been carried out. The primary, secondary, and cumulative patency and other complications between standard thickness (STD) and thin wall (THN) 6 mm stretch ePTFE grafts (WL Gore and Assoc, Flagstaff, AZ) was prospectively evaluated. Methods: From September 1993 to August 1995, 108 patients receiving new grafts were randomized into 2 groups: those receiving STD grafts (n = 56) or those receiving THN (n = 52) grafts. Data prospectively collected included day of first access, primary patency, interventions required, and long-term results. Infections, pseudoaneurysms, and mortality were also documented. Student's unpaired t-test was used to compare the 2 groups, and log-rank life tables were constructed and compared. Results: Mean follow-up examination time was 38.1 ± 0.8 months for STD grafts and 35.1 ± 1.0 months for THN grafts (P<.03). Longer patency was noted in the STD group of grafts (18.2 months for STD vs. 12.1 months for THN). Biographical data and complications, including pseudoaneurysm (6% vs. 5%), infection (2% vs. 3%), and mortality (22% vs. 19%), between STD and THN groups were not different statistically. Mean primary (18.2 months vs. 12.1 months), secondary (20.9 months vs. 13.7 months), and cumulative patency times (22.2 months vs. 15.2 months) for the STD group were significantly more than those for the THN group (P<.000 by log rank of life tables). Other complications were not different between groups. Conclusion: Standard thickness ePTFE is the graft of choice when placing ePTFE arteriovenous grafts for hemodialysis.

Original languageEnglish (US)
Pages (from-to)464-470
Number of pages7
JournalJournal of Vascular Surgery
Volume28
Issue number3
DOIs
StatePublished - Jan 1 1998
Externally publishedYes

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Renal Dialysis
Transplants
Life Tables
False Aneurysm
Mortality
Infection
Fistula
Students

All Science Journal Classification (ASJC) codes

  • Surgery
  • Cardiology and Cardiovascular Medicine

Cite this

A three-year follow-up on standard versus thin wall ePTFE grafts for hemodialysis. / Lenz, B. J.; Veldenz, H. C.; Dennis, J. W.; Khansarinia, S.; Atteberry, L. R.; Goldman, Mitchell.

In: Journal of Vascular Surgery, Vol. 28, No. 3, 01.01.1998, p. 464-470.

Research output: Contribution to journalArticle

Lenz, B. J. ; Veldenz, H. C. ; Dennis, J. W. ; Khansarinia, S. ; Atteberry, L. R. ; Goldman, Mitchell. / A three-year follow-up on standard versus thin wall ePTFE grafts for hemodialysis. In: Journal of Vascular Surgery. 1998 ; Vol. 28, No. 3. pp. 464-470.
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abstract = "Purpose: Expanded polytetraflouroethylene (ePTFE) grafts are the most popular prosthetic grafts for hemodialysis patients in whom autogenous fistulas cannot be constructed. Long-term studies to study the durability and complication rate of the different wall configurations of ePTFE grafts have not been carried out. The primary, secondary, and cumulative patency and other complications between standard thickness (STD) and thin wall (THN) 6 mm stretch ePTFE grafts (WL Gore and Assoc, Flagstaff, AZ) was prospectively evaluated. Methods: From September 1993 to August 1995, 108 patients receiving new grafts were randomized into 2 groups: those receiving STD grafts (n = 56) or those receiving THN (n = 52) grafts. Data prospectively collected included day of first access, primary patency, interventions required, and long-term results. Infections, pseudoaneurysms, and mortality were also documented. Student's unpaired t-test was used to compare the 2 groups, and log-rank life tables were constructed and compared. Results: Mean follow-up examination time was 38.1 ± 0.8 months for STD grafts and 35.1 ± 1.0 months for THN grafts (P<.03). Longer patency was noted in the STD group of grafts (18.2 months for STD vs. 12.1 months for THN). Biographical data and complications, including pseudoaneurysm (6{\%} vs. 5{\%}), infection (2{\%} vs. 3{\%}), and mortality (22{\%} vs. 19{\%}), between STD and THN groups were not different statistically. Mean primary (18.2 months vs. 12.1 months), secondary (20.9 months vs. 13.7 months), and cumulative patency times (22.2 months vs. 15.2 months) for the STD group were significantly more than those for the THN group (P<.000 by log rank of life tables). Other complications were not different between groups. Conclusion: Standard thickness ePTFE is the graft of choice when placing ePTFE arteriovenous grafts for hemodialysis.",
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AU - Lenz, B. J.

AU - Veldenz, H. C.

AU - Dennis, J. W.

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AU - Atteberry, L. R.

AU - Goldman, Mitchell

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N2 - Purpose: Expanded polytetraflouroethylene (ePTFE) grafts are the most popular prosthetic grafts for hemodialysis patients in whom autogenous fistulas cannot be constructed. Long-term studies to study the durability and complication rate of the different wall configurations of ePTFE grafts have not been carried out. The primary, secondary, and cumulative patency and other complications between standard thickness (STD) and thin wall (THN) 6 mm stretch ePTFE grafts (WL Gore and Assoc, Flagstaff, AZ) was prospectively evaluated. Methods: From September 1993 to August 1995, 108 patients receiving new grafts were randomized into 2 groups: those receiving STD grafts (n = 56) or those receiving THN (n = 52) grafts. Data prospectively collected included day of first access, primary patency, interventions required, and long-term results. Infections, pseudoaneurysms, and mortality were also documented. Student's unpaired t-test was used to compare the 2 groups, and log-rank life tables were constructed and compared. Results: Mean follow-up examination time was 38.1 ± 0.8 months for STD grafts and 35.1 ± 1.0 months for THN grafts (P<.03). Longer patency was noted in the STD group of grafts (18.2 months for STD vs. 12.1 months for THN). Biographical data and complications, including pseudoaneurysm (6% vs. 5%), infection (2% vs. 3%), and mortality (22% vs. 19%), between STD and THN groups were not different statistically. Mean primary (18.2 months vs. 12.1 months), secondary (20.9 months vs. 13.7 months), and cumulative patency times (22.2 months vs. 15.2 months) for the STD group were significantly more than those for the THN group (P<.000 by log rank of life tables). Other complications were not different between groups. Conclusion: Standard thickness ePTFE is the graft of choice when placing ePTFE arteriovenous grafts for hemodialysis.

AB - Purpose: Expanded polytetraflouroethylene (ePTFE) grafts are the most popular prosthetic grafts for hemodialysis patients in whom autogenous fistulas cannot be constructed. Long-term studies to study the durability and complication rate of the different wall configurations of ePTFE grafts have not been carried out. The primary, secondary, and cumulative patency and other complications between standard thickness (STD) and thin wall (THN) 6 mm stretch ePTFE grafts (WL Gore and Assoc, Flagstaff, AZ) was prospectively evaluated. Methods: From September 1993 to August 1995, 108 patients receiving new grafts were randomized into 2 groups: those receiving STD grafts (n = 56) or those receiving THN (n = 52) grafts. Data prospectively collected included day of first access, primary patency, interventions required, and long-term results. Infections, pseudoaneurysms, and mortality were also documented. Student's unpaired t-test was used to compare the 2 groups, and log-rank life tables were constructed and compared. Results: Mean follow-up examination time was 38.1 ± 0.8 months for STD grafts and 35.1 ± 1.0 months for THN grafts (P<.03). Longer patency was noted in the STD group of grafts (18.2 months for STD vs. 12.1 months for THN). Biographical data and complications, including pseudoaneurysm (6% vs. 5%), infection (2% vs. 3%), and mortality (22% vs. 19%), between STD and THN groups were not different statistically. Mean primary (18.2 months vs. 12.1 months), secondary (20.9 months vs. 13.7 months), and cumulative patency times (22.2 months vs. 15.2 months) for the STD group were significantly more than those for the THN group (P<.000 by log rank of life tables). Other complications were not different between groups. Conclusion: Standard thickness ePTFE is the graft of choice when placing ePTFE arteriovenous grafts for hemodialysis.

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