A versatile strategy to fabricate hydrogel-silver nanocomposites and investigation of their antimicrobial activity

V. Thomas, Murali Yallapu, B. Sreedhar, S. K. Bajpai

Research output: Contribution to journalArticle

193 Citations (Scopus)

Abstract

In this study, hydrogel-silver nanocomposites have been synthesized by a unique methodology, which involves formation of silver nanoparticles within swollen poly (acrylamide-co-acrylic acid) hydrogels. The formation of silver nanoparticles was confirmed by transmission electron microscopy (TEM) and surface plasmon resonance (SPR) which was obtained at 406 nm. The TEM of hydrogel-silver nanocomposites showed almost uniform distribution of nanoparticles throughout the gel networks. Most of the particles, as revealed from the particle-size distribution curve, were 24-30 nm in size. The X-ray diffraction pattern also confirmed the face centered cubic (fcc) structure of silver nanoparticles. The nanocomposites demonstrated excellent antibacterial effects on Escherichia coli (E. coli). The antibacterial activity depended on size of the nanocomposites, amount of silver nanoparticles, and amount of monomer acid present within the hydrogel-silver nanocomposites. It was also found that immersion of plain hydrogel in 20 mg/30 ml AgNO 3 solution yielded nanocomparticle-hydrogel composites with optimum bactericidal activity.

Original languageEnglish (US)
Pages (from-to)389-395
Number of pages7
JournalJournal of Colloid and Interface Science
Volume315
Issue number1
DOIs
StatePublished - Nov 1 2007

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Hydrogel
Silver
Hydrogels
Nanocomposites
Nanoparticles
Transmission electron microscopy
Acids
Surface plasmon resonance
Polyacrylates
Particle size analysis
Escherichia coli
Diffraction patterns
Particles (particulate matter)
Acrylics
Gels
Monomers
X ray diffraction
Composite materials

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Surfaces, Coatings and Films
  • Colloid and Surface Chemistry

Cite this

A versatile strategy to fabricate hydrogel-silver nanocomposites and investigation of their antimicrobial activity. / Thomas, V.; Yallapu, Murali; Sreedhar, B.; Bajpai, S. K.

In: Journal of Colloid and Interface Science, Vol. 315, No. 1, 01.11.2007, p. 389-395.

Research output: Contribution to journalArticle

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