Abnormal Activation of Temporoparietal Language Areas during Phonetic Analysis in Children with Dyslexia

Joshua I. Breier, Panagiotis G. Simos, Jack M. Fletcher, Eduardo M. Castillo, Wenbo Zhang, Andrew Papanicolaou

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Event-related magnetic fields were recorded using magnetoencephalography in children with (n = 12) and without (n = 11) dyslexia while they discriminated between pairs of syllables from a voice onset time series (/ga/-/ka/). Nonimpaired readers exhibited left-hemisphere predominance of activity after the resolution of the N1m, whereas children with dyslexia experienced a sharp peak of relative activation in right temporoparietal areas between 300 and 700 ms post-stimulus onset. Increased relative activation in right temporoparietal areas was correlated with reduced performance on phonological processing measures. Results are consistent with the notion that deficits in appreciating the sound structure of both written and spoken language are associated with abnormal neurophysiological activity in temporoparietal language areas in children with dyslexia.

Original languageEnglish (US)
Pages (from-to)610-621
Number of pages12
JournalNeuropsychology
Volume17
Issue number4
DOIs
StatePublished - Oct 1 2003

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Dyslexia
Phonetics
Language
Magnetoencephalography
Magnetic Fields

All Science Journal Classification (ASJC) codes

  • Neuropsychology and Physiological Psychology

Cite this

Breier, J. I., Simos, P. G., Fletcher, J. M., Castillo, E. M., Zhang, W., & Papanicolaou, A. (2003). Abnormal Activation of Temporoparietal Language Areas during Phonetic Analysis in Children with Dyslexia. Neuropsychology, 17(4), 610-621. https://doi.org/10.1037/0894-4105.17.4.610

Abnormal Activation of Temporoparietal Language Areas during Phonetic Analysis in Children with Dyslexia. / Breier, Joshua I.; Simos, Panagiotis G.; Fletcher, Jack M.; Castillo, Eduardo M.; Zhang, Wenbo; Papanicolaou, Andrew.

In: Neuropsychology, Vol. 17, No. 4, 01.10.2003, p. 610-621.

Research output: Contribution to journalArticle

Breier, JI, Simos, PG, Fletcher, JM, Castillo, EM, Zhang, W & Papanicolaou, A 2003, 'Abnormal Activation of Temporoparietal Language Areas during Phonetic Analysis in Children with Dyslexia', Neuropsychology, vol. 17, no. 4, pp. 610-621. https://doi.org/10.1037/0894-4105.17.4.610
Breier, Joshua I. ; Simos, Panagiotis G. ; Fletcher, Jack M. ; Castillo, Eduardo M. ; Zhang, Wenbo ; Papanicolaou, Andrew. / Abnormal Activation of Temporoparietal Language Areas during Phonetic Analysis in Children with Dyslexia. In: Neuropsychology. 2003 ; Vol. 17, No. 4. pp. 610-621.
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