Abruptio placentae in cynomolgus macaques (Macaca fascicularis)

Male bias

N. Schlabritz-Loutsevitch, A. Schenone, Mauro Schenone, S. Gupta, G. Hubbard, Jie Zhang, Giancarlo Mari, E. Dick

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: Abruptio placentae is a serious problem with a high rate of maternal and fetal mortality and documented sexual dimorphism in reoccurrence. Macaca fascicularis is a well-described reproductive model; however, there are no data available regarding sexual dimorphism in abruptio placentae in these species. Methods: A retrospective study of pathology and medical records in a large colony of M. fascicularis was performed. Placental specimens were analyzed. Results: The incidence of placenta abruptio in the colony was 15.7/1000 births. In the abruptio placentae group, male fetuses had lower placental disk length and increased femur length compared with female fetuses. The feto-pacental ratio and fetal weight were lower in the male fetuses in the abruption group compared with those in the stillbirth group without abruption placentae. Conclusion: This is the first documentation of male bias in placental and fetal development in abruptio placentae in non-human primates.

Original languageEnglish (US)
Pages (from-to)204-210
Number of pages7
JournalJournal of Medical Primatology
Volume42
Issue number4
DOIs
StatePublished - Aug 1 2013

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Abruptio Placentae
Macaca fascicularis
Macaca
placenta
Fetus
fetus
Sex Characteristics
sexual dimorphism
Fetal Mortality
Placentation
Fetal Weight
Stillbirth
Maternal Mortality
Fetal Development
Documentation
fetal death
Femur
Placenta
Primates
fetal development

All Science Journal Classification (ASJC) codes

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Abruptio placentae in cynomolgus macaques (Macaca fascicularis) : Male bias. / Schlabritz-Loutsevitch, N.; Schenone, A.; Schenone, Mauro; Gupta, S.; Hubbard, G.; Zhang, Jie; Mari, Giancarlo; Dick, E.

In: Journal of Medical Primatology, Vol. 42, No. 4, 01.08.2013, p. 204-210.

Research output: Contribution to journalArticle

Schlabritz-Loutsevitch, N. ; Schenone, A. ; Schenone, Mauro ; Gupta, S. ; Hubbard, G. ; Zhang, Jie ; Mari, Giancarlo ; Dick, E. / Abruptio placentae in cynomolgus macaques (Macaca fascicularis) : Male bias. In: Journal of Medical Primatology. 2013 ; Vol. 42, No. 4. pp. 204-210.
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