Absorption of glucose, amino acids, and dipeptides by the intestines of Atlantic salmon (Salmo salar L.)

A. M. Bakke-McKellep, S. Nordrum, Å Krogdahl, Randal Buddington

Research output: Contribution to journalArticle

68 Citations (Scopus)

Abstract

Rates of glucose, amino acid and dipeptide absorption by the intestine of Atlantic salmon (Salmo salar L.) were measured in vitro at 10 °C as functions of concentration and region using intact tissues (everted sleeve method). Salmon (weight range 300-1300 g) fed a commercial, extruded salmon feed, were kept at 12-13 °C in freshwater. Maximum rates (V(max)) of glucose and dipeptide transport were low compared to most amino acid V(max) values. There was a declining proximal-to-distal gradient of absorption along the post-gastric intestinal tract. A saturable component of absorption was not evident for proline and glycyl-proline in the distal intestine, and glycyl-sarcosine in any region. 'Apparent diffusion', which may include low affinity, high capacity carrier systems and carrier-independent influx, appears to account for the majority to total uptake at higher concentrations of amino acids and dipeptides. There was competition between the dipeptides for transporter sites in the pyloric ceca and mid intestine, suggesting a common carrier. There was also indication of hydrolysis of these dipeptides by brush border membrane enzymes.

Original languageEnglish (US)
Pages (from-to)33-44
Number of pages12
JournalFish Physiology and Biochemistry
Volume22
Issue number1
DOIs
StatePublished - Jan 1 2000
Externally publishedYes

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Salmo salar
dipeptides
Dipeptides
Intestines
glucose
intestines
amino acid
Amino Acids
Glucose
amino acids
Salmon
Proline
salmon
proline
Sarcosine
hydrolysis
Cecum
enzyme
membrane
Brushes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physiology
  • Aquatic Science

Cite this

Absorption of glucose, amino acids, and dipeptides by the intestines of Atlantic salmon (Salmo salar L.). / Bakke-McKellep, A. M.; Nordrum, S.; Krogdahl, Å; Buddington, Randal.

In: Fish Physiology and Biochemistry, Vol. 22, No. 1, 01.01.2000, p. 33-44.

Research output: Contribution to journalArticle

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