Acidulated phosphate fluoride treatment and formation of caries-like lesions in enamel: effect of application time.

Franklin Garcia-Godoy, M. J. Hicks, C. M. Flaitz, J. H. Berg

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The aim of this study was to evaluate the effect of acidulated phosphate fluoride (APF) application time (1 and 4 minutes) on caries-like lesion formation in enamel. Following a fluoride-free prophylaxis, the specimens (10 extracted human molars) were divided into tooth quarters and assigned to treatment groups: 1) Distobuccal and Distolingual Quarters--1 minute APF; 2) Mesiobuccal and Mesiolingual Quarters--4 minute APF. Acid-resistant varnish was applied to the tooth quarters, leaving sound enamel windows exposed on buccal and lingual surfaces. Following treatment, the APF gel (Oral-B Minute Gel) was removed by air-water spray rinsing, followed by a 24-hour water rinse. Sound enamel windows protected from APF treatment by acid-resistant varnish were created adjacent to APF-treated sound enamel windows and served as paired controls. Lesions were created in APF-treated and paired control sound enamel windows with an acidified gel. After lesion formation, sections were obtained and imbibed with water for polarized light study. Body of the lesion depths were measured and compared statistically. Mean body of the lesion depths were: 186 +/- 28 microns for control lesions, 117 +/- 12 microns for APF-1min; and 111 +/- 14 microns for APF-4min. Significant differences (p < 0.05) were found between paired control and APF groups. No difference (p > 0.05) was found between APF-1min and APF-4min groups. APF treatment prior to lesion formation resulted in a significant reduction in lesion depth, regardless of whether a 1 or 4 minute APF treatment period was used. The 1 minute APF treatment provided the same degree of caries protection as the longer treatment period.

Original languageEnglish (US)
Pages (from-to)105-110
Number of pages6
JournalThe Journal of clinical pediatric dentistry
Volume19
Issue number2
StatePublished - Dec 1 1995
Externally publishedYes

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Acidulated Phosphate Fluoride
Dental Enamel
Paint
Gels
Water
Tooth
Acids

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Acidulated phosphate fluoride treatment and formation of caries-like lesions in enamel : effect of application time. / Garcia-Godoy, Franklin; Hicks, M. J.; Flaitz, C. M.; Berg, J. H.

In: The Journal of clinical pediatric dentistry, Vol. 19, No. 2, 01.12.1995, p. 105-110.

Research output: Contribution to journalArticle

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