ACTH-producing pituitary carcinoma presenting as the cauda equina syndrome

A. R. Frost, S. Tenner, M. Tenner, Carlos Rollhauser, S. O. Tabbara

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

A 43-year-old woman presented with incontinence, weakness, and paresthesia, consistent with the cauda equina syndrome, 10 years after having a pituitary tumor surgically removed and 4 years after excision of two 'meningiomas' of the cervical cord. The patient was also hypertensive and had a cushingoid habitus. Emergent surgical decompression of the spinal cord revealed intradural metastatic adrenocorticotropic hormone-producing pituitary carcinoma. Pituitary carcinomas are rare. The majority of reported cases of adrenocorticotropic hormone-producing carcinoma have exhibited metastases outside the central nervous system. To our knowledge, this represents the first case of an adrenocorticotropic hormone-producing pituitary carcinoma presenting with the cauda equina syndrome. A review of all reported cases of pituitary carcinoma indicated that central nervous system metastases were more common than metastases to distant sites, and patients with distant metastases experienced a shorter duration of disease than did those with central nervous system metastases.

Original languageEnglish (US)
Pages (from-to)93-96
Number of pages4
JournalArchives of Pathology and Laboratory Medicine
Volume119
Issue number1
StatePublished - Jan 1 1995
Externally publishedYes

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Polyradiculopathy
Pituitary Neoplasms
Adrenocorticotropic Hormone
Neoplasm Metastasis
Central Nervous System
Surgical Decompression
Paresthesia
Meningioma
Spinal Cord
Carcinoma

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

Cite this

ACTH-producing pituitary carcinoma presenting as the cauda equina syndrome. / Frost, A. R.; Tenner, S.; Tenner, M.; Rollhauser, Carlos; Tabbara, S. O.

In: Archives of Pathology and Laboratory Medicine, Vol. 119, No. 1, 01.01.1995, p. 93-96.

Research output: Contribution to journalArticle

Frost, A. R. ; Tenner, S. ; Tenner, M. ; Rollhauser, Carlos ; Tabbara, S. O. / ACTH-producing pituitary carcinoma presenting as the cauda equina syndrome. In: Archives of Pathology and Laboratory Medicine. 1995 ; Vol. 119, No. 1. pp. 93-96.
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