Adenovirus serotype 14 pneumonia at a basic military training site in the United States, spring 2007

A case series

Lorie Brosch, Juste Tchandja, Vincent Marconi, Mark Rasnake, Vidhya Prakash, Thomas McKnight, Michel Sunning

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Adenovirus, a frequent cause of mild respiratory disease in military trainees, can result in severe manifestations when outbreaks are caused by novel viral strains for which there is little pre-existing immunity. Twentyfive basic military trainees (BMTs) were hospitalized with adenovirus pneumonia from April 1, 2007 through June 21, 2007. Clinical findings for 9 of these patients with PCR-confirmed adenovirus serotype 14 were studied retrospectively. The clinical picture was characterized by cough (88.9%) and sputum production (77.8%). All trainees were febrile. Laboratory results showed 88.9% had normal white blood cell (WBC) counts, 66.7% with high monocytes, and 55.6% with low lymphocytes on differential. All had lobar pneumonia radiographically. One patient required the intensive care unit (ICU) and later expired. In conclusion, among hospitalized patients with the combination of fever, productive cough, normal WBC, a differential showing high monocytes and low lymphocytes in an immunocompetent young adult with lobar pneumonia warrants a high level of suspicion for adenovirus 14 pneumonia.

Original languageEnglish (US)
Pages (from-to)1295-1299
Number of pages5
JournalMilitary Medicine
Volume174
Issue number12
DOIs
StatePublished - Jan 1 2009
Externally publishedYes

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Adenoviridae
Pneumonia
Cough
Monocytes
Fever
Lymphocytes
Sputum
Leukocyte Count
Disease Outbreaks
Intensive Care Units
Young Adult
Immunity
Leukocytes
Polymerase Chain Reaction
Serogroup

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health

Cite this

Adenovirus serotype 14 pneumonia at a basic military training site in the United States, spring 2007 : A case series. / Brosch, Lorie; Tchandja, Juste; Marconi, Vincent; Rasnake, Mark; Prakash, Vidhya; McKnight, Thomas; Sunning, Michel.

In: Military Medicine, Vol. 174, No. 12, 01.01.2009, p. 1295-1299.

Research output: Contribution to journalArticle

Brosch, Lorie ; Tchandja, Juste ; Marconi, Vincent ; Rasnake, Mark ; Prakash, Vidhya ; McKnight, Thomas ; Sunning, Michel. / Adenovirus serotype 14 pneumonia at a basic military training site in the United States, spring 2007 : A case series. In: Military Medicine. 2009 ; Vol. 174, No. 12. pp. 1295-1299.
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