Adherence of cells to myelin basic protein I. Adherence of red and white blood cells from patients with multiple sclerosis to myelin basic protein

J. Najbauer, B. Kosaras, Gabor Tigyi

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Abstract Red blood cells (RBC) and white blood cells (WBC) of patients with multiple sclerosis (MS) show decreased adherence to myelin basic protein (MBP) immobilized on plastic surfaces compared to the binding of cells from patients with other neurological diseases (OND), or such other autoimmune diseases as psoriasis (PS), and to that of healthy controls (HC). No similar phenomenon occurred to basic and non‐basic type proteins other than MBP, for example, to histone (HIS), lysozyme (LYS) and ovalbumin (OVA). Thus, decreased adherence of RBC and WBC in MS patients to MBP appears to be a unique feature of the disease if compared with OND or PS.

Original languageEnglish (US)
Pages (from-to)172-175
Number of pages4
JournalActa Neurologica Scandinavica
Volume76
Issue number3
DOIs
StatePublished - Jan 1 1987

Fingerprint

Myelin Basic Protein
Multiple Sclerosis
Leukocytes
Erythrocytes
Psoriasis
Ovalbumin
Muramidase
Histones
Autoimmune Diseases
Plastics
basic protein I
Proteins

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

Cite this

Adherence of cells to myelin basic protein I. Adherence of red and white blood cells from patients with multiple sclerosis to myelin basic protein. / Najbauer, J.; Kosaras, B.; Tigyi, Gabor.

In: Acta Neurologica Scandinavica, Vol. 76, No. 3, 01.01.1987, p. 172-175.

Research output: Contribution to journalArticle

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AB - Abstract Red blood cells (RBC) and white blood cells (WBC) of patients with multiple sclerosis (MS) show decreased adherence to myelin basic protein (MBP) immobilized on plastic surfaces compared to the binding of cells from patients with other neurological diseases (OND), or such other autoimmune diseases as psoriasis (PS), and to that of healthy controls (HC). No similar phenomenon occurred to basic and non‐basic type proteins other than MBP, for example, to histone (HIS), lysozyme (LYS) and ovalbumin (OVA). Thus, decreased adherence of RBC and WBC in MS patients to MBP appears to be a unique feature of the disease if compared with OND or PS.

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