Alteration of serum monoamine level and brain electrical activity in stress and hypertension by Black tea

Debjani Guha, Purnima Singh, Ranita Ganguly, Dipanjan Saha, Debasis Biswas, Rimi Hazra, Kausik Ray

Research output: Contribution to journalArticle

Abstract

Effect of chronic treatment of standardized hot water extract of Camellia sinensis (BTE) for 14 days on stress and hypertensive models of rat, behavioural (learning and memory) testing (Shuttle box avoidance test), brain EEG activity and serum neurotransmitter (NE, 5-HT, DA) was studied in male Charles Foster strain rats. The result revealed that oral pretreatment with BTE (5ml/kg) markedly increase in the performance of active avoidance learning in the Shuttle box avoidance test. Electroencephalographic recording showed that BTE pretreatment to experimental animals elicited significant decrease in β-waves and increase in α-waves. It also resulted in the elevation of serum serotonin (5-HT) level and significant decrease in norepinephrine (NE) level. The present study suggests that chronic administration of BTE helps in combating stress and hypertension possibly by altering serum monoamine level.

Original languageEnglish (US)
Pages (from-to)137-147
Number of pages11
JournalBiogenic Amines
Volume21
Issue number3
StatePublished - Dec 1 2007

Fingerprint

Tea
Serotonin
Hypertension
Norepinephrine
Brain
Serum
Camellia sinensis
Avoidance Learning
Problem-Based Learning
Neurotransmitter Agents
Electroencephalography
Learning
Water

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Pharmacology

Cite this

Guha, D., Singh, P., Ganguly, R., Saha, D., Biswas, D., Hazra, R., & Ray, K. (2007). Alteration of serum monoamine level and brain electrical activity in stress and hypertension by Black tea. Biogenic Amines, 21(3), 137-147.

Alteration of serum monoamine level and brain electrical activity in stress and hypertension by Black tea. / Guha, Debjani; Singh, Purnima; Ganguly, Ranita; Saha, Dipanjan; Biswas, Debasis; Hazra, Rimi; Ray, Kausik.

In: Biogenic Amines, Vol. 21, No. 3, 01.12.2007, p. 137-147.

Research output: Contribution to journalArticle

Guha, D, Singh, P, Ganguly, R, Saha, D, Biswas, D, Hazra, R & Ray, K 2007, 'Alteration of serum monoamine level and brain electrical activity in stress and hypertension by Black tea', Biogenic Amines, vol. 21, no. 3, pp. 137-147.
Guha, Debjani ; Singh, Purnima ; Ganguly, Ranita ; Saha, Dipanjan ; Biswas, Debasis ; Hazra, Rimi ; Ray, Kausik. / Alteration of serum monoamine level and brain electrical activity in stress and hypertension by Black tea. In: Biogenic Amines. 2007 ; Vol. 21, No. 3. pp. 137-147.
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