Altering the Brain Circuits for Reading Through Intervention

A Magnetic Source Imaging Study

Panagiotis G. Simos, Jack M. Fletcher, Shirin Sarkari, Rebecca L. Billingsley, Carolyn Denton, Andrew Papanicolaou

Research output: Contribution to journalArticle

69 Citations (Scopus)

Abstract

Intervention-related changes in spatiotemporal profiles of regional brain activation were examined by whole-head magnetoencephalography in 15 children with severe reading difficulties who had failed to show adequate progress to quality reading instruction during Grade 1. Intensive intervention initially focused on phonological decoding skills (for 8 weeks) and, during the subsequent 8 weeks, on rapid word recognition ability. Clinically significant improvement in reading skills was noted in 8 children who showed "normalizing" changes in their spatiotemporal profiles of regional brain activity (increased duration of activity in the left temporoparietal region and a shift in the relative timing of activity in temporoparietal and inferior frontal regions). Seven children who demonstrated "compensatory" changes in brain activity (increased duration of activity in the right temporoparietal region and frontal areas, bilaterally) did not show adequate response to intervention. Nonimpaired readers did not show systematic changes in brain activity across visits.

Original languageEnglish (US)
Pages (from-to)485-496
Number of pages12
JournalNeuropsychology
Volume21
Issue number4
DOIs
StatePublished - Jul 1 2007

Fingerprint

Reading
Brain
Magnetoencephalography
Head

All Science Journal Classification (ASJC) codes

  • Neuropsychology and Physiological Psychology

Cite this

Simos, P. G., Fletcher, J. M., Sarkari, S., Billingsley, R. L., Denton, C., & Papanicolaou, A. (2007). Altering the Brain Circuits for Reading Through Intervention: A Magnetic Source Imaging Study. Neuropsychology, 21(4), 485-496. https://doi.org/10.1037/0894-4105.21.4.485

Altering the Brain Circuits for Reading Through Intervention : A Magnetic Source Imaging Study. / Simos, Panagiotis G.; Fletcher, Jack M.; Sarkari, Shirin; Billingsley, Rebecca L.; Denton, Carolyn; Papanicolaou, Andrew.

In: Neuropsychology, Vol. 21, No. 4, 01.07.2007, p. 485-496.

Research output: Contribution to journalArticle

Simos, PG, Fletcher, JM, Sarkari, S, Billingsley, RL, Denton, C & Papanicolaou, A 2007, 'Altering the Brain Circuits for Reading Through Intervention: A Magnetic Source Imaging Study', Neuropsychology, vol. 21, no. 4, pp. 485-496. https://doi.org/10.1037/0894-4105.21.4.485
Simos PG, Fletcher JM, Sarkari S, Billingsley RL, Denton C, Papanicolaou A. Altering the Brain Circuits for Reading Through Intervention: A Magnetic Source Imaging Study. Neuropsychology. 2007 Jul 1;21(4):485-496. https://doi.org/10.1037/0894-4105.21.4.485
Simos, Panagiotis G. ; Fletcher, Jack M. ; Sarkari, Shirin ; Billingsley, Rebecca L. ; Denton, Carolyn ; Papanicolaou, Andrew. / Altering the Brain Circuits for Reading Through Intervention : A Magnetic Source Imaging Study. In: Neuropsychology. 2007 ; Vol. 21, No. 4. pp. 485-496.
@article{9a3d31f17d5742e9a4fab5ce97a46727,
title = "Altering the Brain Circuits for Reading Through Intervention: A Magnetic Source Imaging Study",
abstract = "Intervention-related changes in spatiotemporal profiles of regional brain activation were examined by whole-head magnetoencephalography in 15 children with severe reading difficulties who had failed to show adequate progress to quality reading instruction during Grade 1. Intensive intervention initially focused on phonological decoding skills (for 8 weeks) and, during the subsequent 8 weeks, on rapid word recognition ability. Clinically significant improvement in reading skills was noted in 8 children who showed {"}normalizing{"} changes in their spatiotemporal profiles of regional brain activity (increased duration of activity in the left temporoparietal region and a shift in the relative timing of activity in temporoparietal and inferior frontal regions). Seven children who demonstrated {"}compensatory{"} changes in brain activity (increased duration of activity in the right temporoparietal region and frontal areas, bilaterally) did not show adequate response to intervention. Nonimpaired readers did not show systematic changes in brain activity across visits.",
author = "Simos, {Panagiotis G.} and Fletcher, {Jack M.} and Shirin Sarkari and Billingsley, {Rebecca L.} and Carolyn Denton and Andrew Papanicolaou",
year = "2007",
month = "7",
day = "1",
doi = "10.1037/0894-4105.21.4.485",
language = "English (US)",
volume = "21",
pages = "485--496",
journal = "Neuropsychology",
issn = "0894-4105",
publisher = "American Psychological Association Inc.",
number = "4",

}

TY - JOUR

T1 - Altering the Brain Circuits for Reading Through Intervention

T2 - A Magnetic Source Imaging Study

AU - Simos, Panagiotis G.

AU - Fletcher, Jack M.

AU - Sarkari, Shirin

AU - Billingsley, Rebecca L.

AU - Denton, Carolyn

AU - Papanicolaou, Andrew

PY - 2007/7/1

Y1 - 2007/7/1

N2 - Intervention-related changes in spatiotemporal profiles of regional brain activation were examined by whole-head magnetoencephalography in 15 children with severe reading difficulties who had failed to show adequate progress to quality reading instruction during Grade 1. Intensive intervention initially focused on phonological decoding skills (for 8 weeks) and, during the subsequent 8 weeks, on rapid word recognition ability. Clinically significant improvement in reading skills was noted in 8 children who showed "normalizing" changes in their spatiotemporal profiles of regional brain activity (increased duration of activity in the left temporoparietal region and a shift in the relative timing of activity in temporoparietal and inferior frontal regions). Seven children who demonstrated "compensatory" changes in brain activity (increased duration of activity in the right temporoparietal region and frontal areas, bilaterally) did not show adequate response to intervention. Nonimpaired readers did not show systematic changes in brain activity across visits.

AB - Intervention-related changes in spatiotemporal profiles of regional brain activation were examined by whole-head magnetoencephalography in 15 children with severe reading difficulties who had failed to show adequate progress to quality reading instruction during Grade 1. Intensive intervention initially focused on phonological decoding skills (for 8 weeks) and, during the subsequent 8 weeks, on rapid word recognition ability. Clinically significant improvement in reading skills was noted in 8 children who showed "normalizing" changes in their spatiotemporal profiles of regional brain activity (increased duration of activity in the left temporoparietal region and a shift in the relative timing of activity in temporoparietal and inferior frontal regions). Seven children who demonstrated "compensatory" changes in brain activity (increased duration of activity in the right temporoparietal region and frontal areas, bilaterally) did not show adequate response to intervention. Nonimpaired readers did not show systematic changes in brain activity across visits.

UR - http://www.scopus.com/inward/record.url?scp=34548156748&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34548156748&partnerID=8YFLogxK

U2 - 10.1037/0894-4105.21.4.485

DO - 10.1037/0894-4105.21.4.485

M3 - Article

VL - 21

SP - 485

EP - 496

JO - Neuropsychology

JF - Neuropsychology

SN - 0894-4105

IS - 4

ER -