Anti-inflammatory approaches to ischaemic stroke prevention

Peter J. Kelly, Sean Murphy, Sarah Coveney, Francisco Purroy, Robin Lemmens, Georgios Tsivgoulis, Chris Price

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

Stroke is a major cause of neurological morbidity and mortality. Atherosclerosis is a major contributor to first and recurrent stroke. A growing evidence base indicates that inflammation is a key process in the pathogenesis of atherosclerosis, leading to thromboembolic events. In this review, we summarise the evidence linking inflammation to stroke risk and discuss clinical trials addressing the 'inflammation hypothesis' in coronary disease and stroke. Trial registration number CONVINCE trial ClinicalTrials.gov number; NCT 02898610; Pre-results.

Original languageEnglish (US)
Pages (from-to)211-218
Number of pages8
JournalJournal of Neurology, Neurosurgery and Psychiatry
Volume89
Issue number2
DOIs
StatePublished - Feb 1 2018

Fingerprint

Anti-Inflammatory Agents
Stroke
Inflammation
Atherosclerosis
Coronary Disease
Clinical Trials
Morbidity
Mortality

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology
  • Psychiatry and Mental health

Cite this

Anti-inflammatory approaches to ischaemic stroke prevention. / Kelly, Peter J.; Murphy, Sean; Coveney, Sarah; Purroy, Francisco; Lemmens, Robin; Tsivgoulis, Georgios; Price, Chris.

In: Journal of Neurology, Neurosurgery and Psychiatry, Vol. 89, No. 2, 01.02.2018, p. 211-218.

Research output: Contribution to journalReview article

Kelly, Peter J. ; Murphy, Sean ; Coveney, Sarah ; Purroy, Francisco ; Lemmens, Robin ; Tsivgoulis, Georgios ; Price, Chris. / Anti-inflammatory approaches to ischaemic stroke prevention. In: Journal of Neurology, Neurosurgery and Psychiatry. 2018 ; Vol. 89, No. 2. pp. 211-218.
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