Antibody to the Retrovirus Associated With the Acquired Immunodeficiency Syndrome (AIDS): Presence in Presumably Healthy San Franciscans Who Died Unexpectedly

Diana Lewis Coleman, John M. Luce, Judith C. Wilber, Jose J. Ferrer, Boyd G. Stephens, William Margaretten, Elizabeth A. Wagar, W. Keith Hadley, Linda Pifer, Andrew R. Moss, Peter M. Dodek, Jay A. Levy, John F. Murray

Research output: Contribution to journalArticle

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Abstract

• We performed autopsies and serologic tests in 189 subjects (152 men and 37 women) between 20 and 50 years of age with no history of immunosuppression who died unexpectedly and whose bodies were referred to the San Francisco coroner’s office. Forty-eight of the 88 single men for whom addresses were available lived in areas of the city with a high incidence of the acquired immunodeficiency syndrome (AIDS). In addition, 36 of the subjects (30 men) were intravenous drug abusers. Antibody to the retrovirus associated with AIDS was present in 23 (18%) of the 121 subjects whose sera were tested. However, neither pathologic nor laboratory manifestations of AIDS were present in any of the 189 subjects who underwent autopsy. These results suggest that antibody to the retrovirus is common but subclinical manifestations of AIDS are uncommon in San Francisco, a city where the incidence of clinical AIDS is high.

Original languageEnglish (US)
Pages (from-to)713-715
Number of pages3
JournalArchives of Internal Medicine
Volume146
Issue number4
DOIs
StatePublished - Jan 1 1986

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Retroviridae
Acquired Immunodeficiency Syndrome
Antibodies
San Francisco
Autopsy
Coroners and Medical Examiners
Incidence
Serologic Tests
Drug Users
Immunosuppression
Serum

All Science Journal Classification (ASJC) codes

  • Internal Medicine

Cite this

Antibody to the Retrovirus Associated With the Acquired Immunodeficiency Syndrome (AIDS) : Presence in Presumably Healthy San Franciscans Who Died Unexpectedly. / Coleman, Diana Lewis; Luce, John M.; Wilber, Judith C.; Ferrer, Jose J.; Stephens, Boyd G.; Margaretten, William; Wagar, Elizabeth A.; Hadley, W. Keith; Pifer, Linda; Moss, Andrew R.; Dodek, Peter M.; Levy, Jay A.; Murray, John F.

In: Archives of Internal Medicine, Vol. 146, No. 4, 01.01.1986, p. 713-715.

Research output: Contribution to journalArticle

Coleman, DL, Luce, JM, Wilber, JC, Ferrer, JJ, Stephens, BG, Margaretten, W, Wagar, EA, Hadley, WK, Pifer, L, Moss, AR, Dodek, PM, Levy, JA & Murray, JF 1986, 'Antibody to the Retrovirus Associated With the Acquired Immunodeficiency Syndrome (AIDS): Presence in Presumably Healthy San Franciscans Who Died Unexpectedly', Archives of Internal Medicine, vol. 146, no. 4, pp. 713-715. https://doi.org/10.1001/archinte.1986.00360160137018
Coleman, Diana Lewis ; Luce, John M. ; Wilber, Judith C. ; Ferrer, Jose J. ; Stephens, Boyd G. ; Margaretten, William ; Wagar, Elizabeth A. ; Hadley, W. Keith ; Pifer, Linda ; Moss, Andrew R. ; Dodek, Peter M. ; Levy, Jay A. ; Murray, John F. / Antibody to the Retrovirus Associated With the Acquired Immunodeficiency Syndrome (AIDS) : Presence in Presumably Healthy San Franciscans Who Died Unexpectedly. In: Archives of Internal Medicine. 1986 ; Vol. 146, No. 4. pp. 713-715.
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