Antimicrobial stewardship impact on Pseudomonas aeruginosa susceptibility to meropenem at a tertiary pediatric institution

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Abstract

An antimicrobial stewardship program was implemented throughout 2012 at a tertiary pediatric institution with guideline development preceding prospective audit and feedback starting in 2013. Meropenem use decreased over 62% during the next 5 years. Non-cystic fibrosis Pseudomonas aeruginosa isolate susceptibility to meropenem increased from 89% in 2011 to 98% in 2017 (P <.001) and correlated with meropenem use the preceding year (Rs: −0.78, P =.008).

Original languageEnglish (US)
JournalAmerican Journal of Infection Control
DOIs
StatePublished - Jan 1 2019

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meropenem
Pseudomonas aeruginosa
Pediatrics
Fibrosis
Guidelines

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Health Policy
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Cite this

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title = "Antimicrobial stewardship impact on Pseudomonas aeruginosa susceptibility to meropenem at a tertiary pediatric institution",
abstract = "An antimicrobial stewardship program was implemented throughout 2012 at a tertiary pediatric institution with guideline development preceding prospective audit and feedback starting in 2013. Meropenem use decreased over 62{\%} during the next 5 years. Non-cystic fibrosis Pseudomonas aeruginosa isolate susceptibility to meropenem increased from 89{\%} in 2011 to 98{\%} in 2017 (P <.001) and correlated with meropenem use the preceding year (Rs: −0.78, P =.008).",
author = "Jeremy Stultz and Sandra Arnold and Chasity Shelton and Bindiya Bagga and Kelley Lee",
year = "2019",
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