Approximate volumetric system models for microSPECT

Jens Gregor, S. Gleason, Stephen Kennel, M. Paulus, T. Benson, Jonathan Wall

Research output: Contribution to journalConference article

5 Citations (Scopus)

Abstract

A microSPECT system is being developed for the purpose of studying murine models of amyloidosis in vivo. The system is equipped with two detector heads, each consisting of a multi-anode photomultiplier tube coupled to a pixellated NaI(Tl) crystal array. Images are reconstructed using an OS-EM algorithm. In this paper, we describe the associated volumetric system models that we have developed in support of both pinhole and parallel hole collimation. These models, which are precompiled and stored to disk prior to reconstruction, are based on simple inner-product computations and a region-growing like search defined by the conic view that each detector pixel has of the image voxels. We provide illustrative experimental results based on phantom and mouse data.

Original languageEnglish (US)
Pages (from-to)2475-2478
Number of pages4
JournalIEEE Nuclear Science Symposium Conference Record
Volume4
StatePublished - Dec 1 2004
Externally publishedYes

Fingerprint

Amyloidosis
Electrodes
Head
detectors
collimation
photomultiplier tubes
pinholes
mice
anodes
pixels
products
crystals
thallium-doped sodium iodide

All Science Journal Classification (ASJC) codes

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging

Cite this

Approximate volumetric system models for microSPECT. / Gregor, Jens; Gleason, S.; Kennel, Stephen; Paulus, M.; Benson, T.; Wall, Jonathan.

In: IEEE Nuclear Science Symposium Conference Record, Vol. 4, 01.12.2004, p. 2475-2478.

Research output: Contribution to journalConference article

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