Approximate volumetric system models for MicroSPECT

Jens Gregor, T. Benson, S. Gleason, M. Paulus, S. Figueroa, T. Hoffman, Stephen Kennel, Jonathan Wall

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A microSPECT system has been developed for the purpose of studying murine models of amyloidosis in vivo. The system is equipped with two detector heads, each consisting of a multi-anode photomultiplier tube coupled to a pixellated NaI(Tl) crystal array. Images are reconstructed using an OS-EM algorithm. In this paper, we describe the associated volumetric system models that we have developed in support of both pinhole and parallel hole collimation. These models, which are precomputed and stored to disk prior to reconstruction, are based on simple inner-product computations and a region-growing like search defined by the conic view that each detector pixel has of the image voxels. We provide illustrative experimental results based on phantom and mouse data.

Original languageEnglish (US)
Article number1710250
Pages (from-to)2646-2652
Number of pages7
JournalIEEE Transactions on Nuclear Science
Volume53
Issue number5
DOIs
StatePublished - Oct 1 2006
Externally publishedYes

Fingerprint

Detectors
Electron tubes
Photomultipliers
detectors
collimation
photomultiplier tubes
pinholes
mice
Anodes
anodes
Pixels
pixels
Crystals
products
crystals

All Science Journal Classification (ASJC) codes

  • Nuclear and High Energy Physics
  • Nuclear Energy and Engineering
  • Electrical and Electronic Engineering

Cite this

Gregor, J., Benson, T., Gleason, S., Paulus, M., Figueroa, S., Hoffman, T., ... Wall, J. (2006). Approximate volumetric system models for MicroSPECT. IEEE Transactions on Nuclear Science, 53(5), 2646-2652. [1710250]. https://doi.org/10.1109/TNS.2006.882774

Approximate volumetric system models for MicroSPECT. / Gregor, Jens; Benson, T.; Gleason, S.; Paulus, M.; Figueroa, S.; Hoffman, T.; Kennel, Stephen; Wall, Jonathan.

In: IEEE Transactions on Nuclear Science, Vol. 53, No. 5, 1710250, 01.10.2006, p. 2646-2652.

Research output: Contribution to journalArticle

Gregor, J, Benson, T, Gleason, S, Paulus, M, Figueroa, S, Hoffman, T, Kennel, S & Wall, J 2006, 'Approximate volumetric system models for MicroSPECT', IEEE Transactions on Nuclear Science, vol. 53, no. 5, 1710250, pp. 2646-2652. https://doi.org/10.1109/TNS.2006.882774
Gregor J, Benson T, Gleason S, Paulus M, Figueroa S, Hoffman T et al. Approximate volumetric system models for MicroSPECT. IEEE Transactions on Nuclear Science. 2006 Oct 1;53(5):2646-2652. 1710250. https://doi.org/10.1109/TNS.2006.882774
Gregor, Jens ; Benson, T. ; Gleason, S. ; Paulus, M. ; Figueroa, S. ; Hoffman, T. ; Kennel, Stephen ; Wall, Jonathan. / Approximate volumetric system models for MicroSPECT. In: IEEE Transactions on Nuclear Science. 2006 ; Vol. 53, No. 5. pp. 2646-2652.
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