Asymmetric synthesis of alkylarylcarbinols via reaction of a chiral pinanediol alkylboronic ester with arylmethyl chlorides

George Kabalka, Nan Sheng Li, Su Yu

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The reaction of arylmethyl chlorides with chiral pinanediol esters of alkylboronic acids in the presence of lithium dicyclohexylamide affords chiral alkylarylcarbinols in good stereochemical yields after oxidation.

Original languageEnglish (US)
Pages (from-to)3843-3846
Number of pages4
JournalTetrahedron Asymmetry
Volume8
Issue number23
DOIs
StatePublished - Dec 11 1997
Externally publishedYes

Fingerprint

Lithium
Chlorides
esters
Esters
lithium
chlorides
Oxidation
oxidation
acids
Acids
synthesis

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

Cite this

Asymmetric synthesis of alkylarylcarbinols via reaction of a chiral pinanediol alkylboronic ester with arylmethyl chlorides. / Kabalka, George; Li, Nan Sheng; Yu, Su.

In: Tetrahedron Asymmetry, Vol. 8, No. 23, 11.12.1997, p. 3843-3846.

Research output: Contribution to journalArticle

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abstract = "The reaction of arylmethyl chlorides with chiral pinanediol esters of alkylboronic acids in the presence of lithium dicyclohexylamide affords chiral alkylarylcarbinols in good stereochemical yields after oxidation.",
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