ATP degradation products after ischemic exercise

Hereditary lack of phosphorylase or carnitine palmityltransferase

Tulio Bertorini, Vera Shively, Bonnie Taylor, Genaro M.A. Palmieri, Irving H. Fox

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

We measured purine degradation products of ATP in plasma after ischemic exercise in eight normal subjects, one patient with myophosphorylase deficiency (McArdle’s disease), and one with carnitine palmityltransferase deficiency. Normal subjects increase hypoxanthine and inosine, but not xanthine. Plasma purine levels were elevated above the normal range after ischemic exercise in McArdle’s disease and in carnitine palmityltransferase deficiency after fasting. Those changes implied abnormally accelerated ATP degradation in these two myopathies.

Original languageEnglish (US)
Pages (from-to)1355-1357
Number of pages3
JournalNeurology
Volume35
Issue number9
StatePublished - Jan 1 1985

Fingerprint

Glycogen Storage Disease Type V
Phosphorylases
Carnitine
Adenosine Triphosphate
Exercise
Deficiency Diseases
Inosine
Hypoxanthine
Xanthine
Muscular Diseases
Fasting
Reference Values
purine

All Science Journal Classification (ASJC) codes

  • Clinical Neurology

Cite this

ATP degradation products after ischemic exercise : Hereditary lack of phosphorylase or carnitine palmityltransferase. / Bertorini, Tulio; Shively, Vera; Taylor, Bonnie; Palmieri, Genaro M.A.; Fox, Irving H.

In: Neurology, Vol. 35, No. 9, 01.01.1985, p. 1355-1357.

Research output: Contribution to journalArticle

Bertorini, T, Shively, V, Taylor, B, Palmieri, GMA & Fox, IH 1985, 'ATP degradation products after ischemic exercise: Hereditary lack of phosphorylase or carnitine palmityltransferase', Neurology, vol. 35, no. 9, pp. 1355-1357.
Bertorini, Tulio ; Shively, Vera ; Taylor, Bonnie ; Palmieri, Genaro M.A. ; Fox, Irving H. / ATP degradation products after ischemic exercise : Hereditary lack of phosphorylase or carnitine palmityltransferase. In: Neurology. 1985 ; Vol. 35, No. 9. pp. 1355-1357.
@article{d38a3d54000f4be88c743cba5e10b3f7,
title = "ATP degradation products after ischemic exercise: Hereditary lack of phosphorylase or carnitine palmityltransferase",
abstract = "We measured purine degradation products of ATP in plasma after ischemic exercise in eight normal subjects, one patient with myophosphorylase deficiency (McArdle’s disease), and one with carnitine palmityltransferase deficiency. Normal subjects increase hypoxanthine and inosine, but not xanthine. Plasma purine levels were elevated above the normal range after ischemic exercise in McArdle’s disease and in carnitine palmityltransferase deficiency after fasting. Those changes implied abnormally accelerated ATP degradation in these two myopathies.",
author = "Tulio Bertorini and Vera Shively and Bonnie Taylor and Palmieri, {Genaro M.A.} and Fox, {Irving H.}",
year = "1985",
month = "1",
day = "1",
language = "English (US)",
volume = "35",
pages = "1355--1357",
journal = "Neurology",
issn = "0028-3878",
publisher = "Lippincott Williams and Wilkins",
number = "9",

}

TY - JOUR

T1 - ATP degradation products after ischemic exercise

T2 - Hereditary lack of phosphorylase or carnitine palmityltransferase

AU - Bertorini, Tulio

AU - Shively, Vera

AU - Taylor, Bonnie

AU - Palmieri, Genaro M.A.

AU - Fox, Irving H.

PY - 1985/1/1

Y1 - 1985/1/1

N2 - We measured purine degradation products of ATP in plasma after ischemic exercise in eight normal subjects, one patient with myophosphorylase deficiency (McArdle’s disease), and one with carnitine palmityltransferase deficiency. Normal subjects increase hypoxanthine and inosine, but not xanthine. Plasma purine levels were elevated above the normal range after ischemic exercise in McArdle’s disease and in carnitine palmityltransferase deficiency after fasting. Those changes implied abnormally accelerated ATP degradation in these two myopathies.

AB - We measured purine degradation products of ATP in plasma after ischemic exercise in eight normal subjects, one patient with myophosphorylase deficiency (McArdle’s disease), and one with carnitine palmityltransferase deficiency. Normal subjects increase hypoxanthine and inosine, but not xanthine. Plasma purine levels were elevated above the normal range after ischemic exercise in McArdle’s disease and in carnitine palmityltransferase deficiency after fasting. Those changes implied abnormally accelerated ATP degradation in these two myopathies.

UR - http://www.scopus.com/inward/record.url?scp=0021868187&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021868187&partnerID=8YFLogxK

M3 - Article

VL - 35

SP - 1355

EP - 1357

JO - Neurology

JF - Neurology

SN - 0028-3878

IS - 9

ER -