Azithromycin inhibits macrophage tumor necrosis factor secretion in response to both azithromycin-susceptible and azithromycin-resistant pneumococci

Kim Ingram, Matthew Marker, Elizabeth Meals, Ajay Talati, Thomas Spentzas, B. Keith English

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We studied the effect of azithromycin (AZM) on macrophage responses to pneumococci.We found that exposure of pneumococci to AZM led to reduced tumor necrosis factor (TNF) secretion by macrophages; this effect was observed in response to both AZM-susceptible and AZM-resistant (AZM-R) pneumococci.

Original languageEnglish (US)
Article numberpit014
Pages (from-to)168-171
Number of pages4
JournalJournal of the Pediatric Infectious Diseases Society
Volume3
Issue number2
DOIs
StatePublished - Jan 1 2014

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Azithromycin
Streptococcus pneumoniae
Tumor Necrosis Factor-alpha
Macrophages

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Infectious Diseases

Cite this

Azithromycin inhibits macrophage tumor necrosis factor secretion in response to both azithromycin-susceptible and azithromycin-resistant pneumococci. / Ingram, Kim; Marker, Matthew; Meals, Elizabeth; Talati, Ajay; Spentzas, Thomas; Keith English, B.

In: Journal of the Pediatric Infectious Diseases Society, Vol. 3, No. 2, pit014, 01.01.2014, p. 168-171.

Research output: Contribution to journalArticle

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