Baseline predictors of missed visits in the look AHEAD study

Stephanie L. Fitzpatrick, Robert Jeffery, Karen Johnson, Cathy C. Roche, Brent Van Dorsten, Molly Gee, Ruby Ann Johnson, Jeanne Charleston, Kathy Dotson, Michael P. Walkup, Felicia Hill-Briggs, Frederick L. Brancati

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Objective To identify baseline attributes associated with consecutively missed data collection visits during the first 48 months of Look AHEAD - a randomized, controlled trial in 5,145 overweight/obese adults with type 2 diabetes designed to determine the long-term health benefits of weight loss achieved by lifestyle change. Design and Methods The analyzed sample consisted of 5,016 participants who were alive at month 48 and enrolled at Look AHEAD sites. Demographic, baseline behavior, psychosocial factors, and treatment randomization were included as predictors of missed consecutive visits in proportional hazard models. Results In multivariate Cox proportional hazard models, baseline attributes of participants who missed consecutive visits (n = 222) included: younger age (hazard ratio [HR] 1.18 per 5 years younger; 95% confidence Interval 1.05, 1.30), higher depression score (HR 1.04; 1.01, 1.06), non-married status (HR 1.37; 1.04, 1.82), never self-weighing prior to enrollment (HR 2.01; 1.25, 3.23), and randomization to minimal vs. intensive lifestyle intervention (HR 1.46; 1.11, 1.91). Conclusions Younger age, symptoms of depression, non-married status, never self-weighing, and randomization to minimal intervention were associated with a higher likelihood of missing consecutive data collection visits, even in a high-retention trial like Look AHEAD. Whether modifications to screening or retention efforts targeted to these attributes might enhance long-term retention in behavioral trials requires further investigation.

Original languageEnglish (US)
Pages (from-to)131-140
Number of pages10
JournalObesity
Volume22
Issue number1
DOIs
StatePublished - Jan 1 2014

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Random Allocation
Proportional Hazards Models
Life Style
Depression
Insurance Benefits
Type 2 Diabetes Mellitus
Weight Loss
Randomized Controlled Trials
Demography
Confidence Intervals
Psychology
Therapeutics

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Nutrition and Dietetics

Cite this

Fitzpatrick, S. L., Jeffery, R., Johnson, K., Roche, C. C., Van Dorsten, B., Gee, M., ... Brancati, F. L. (2014). Baseline predictors of missed visits in the look AHEAD study. Obesity, 22(1), 131-140. https://doi.org/10.1002/oby.20613

Baseline predictors of missed visits in the look AHEAD study. / Fitzpatrick, Stephanie L.; Jeffery, Robert; Johnson, Karen; Roche, Cathy C.; Van Dorsten, Brent; Gee, Molly; Johnson, Ruby Ann; Charleston, Jeanne; Dotson, Kathy; Walkup, Michael P.; Hill-Briggs, Felicia; Brancati, Frederick L.

In: Obesity, Vol. 22, No. 1, 01.01.2014, p. 131-140.

Research output: Contribution to journalArticle

Fitzpatrick, SL, Jeffery, R, Johnson, K, Roche, CC, Van Dorsten, B, Gee, M, Johnson, RA, Charleston, J, Dotson, K, Walkup, MP, Hill-Briggs, F & Brancati, FL 2014, 'Baseline predictors of missed visits in the look AHEAD study', Obesity, vol. 22, no. 1, pp. 131-140. https://doi.org/10.1002/oby.20613
Fitzpatrick SL, Jeffery R, Johnson K, Roche CC, Van Dorsten B, Gee M et al. Baseline predictors of missed visits in the look AHEAD study. Obesity. 2014 Jan 1;22(1):131-140. https://doi.org/10.1002/oby.20613
Fitzpatrick, Stephanie L. ; Jeffery, Robert ; Johnson, Karen ; Roche, Cathy C. ; Van Dorsten, Brent ; Gee, Molly ; Johnson, Ruby Ann ; Charleston, Jeanne ; Dotson, Kathy ; Walkup, Michael P. ; Hill-Briggs, Felicia ; Brancati, Frederick L. / Baseline predictors of missed visits in the look AHEAD study. In: Obesity. 2014 ; Vol. 22, No. 1. pp. 131-140.
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