Baylis-Hillman chemistry

A one pot cross-coupling/allylboration reaction

George Kabalka, Bollu Venkataiah, Gang Dong

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

A one pot sequential cross-coupling/allylboration is described. Baylis-Hillman acetate adducts couple with bis(pinacolato)diboron to form substituted allylboronates, which react with aldehydes in the presence of a silica supported BF3 catalyst to form highly functionalized homoallylic alcohols in excellent yields.

Original languageEnglish (US)
Pages (from-to)4209-4211
Number of pages3
JournalTetrahedron Letters
Volume46
Issue number24
DOIs
StatePublished - Jun 13 2005

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Catalyst supports
Aldehydes
Silicon Dioxide
Acetates
Alcohols
bis(pinacolato)diboron

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Baylis-Hillman chemistry : A one pot cross-coupling/allylboration reaction. / Kabalka, George; Venkataiah, Bollu; Dong, Gang.

In: Tetrahedron Letters, Vol. 46, No. 24, 13.06.2005, p. 4209-4211.

Research output: Contribution to journalArticle

Kabalka, George ; Venkataiah, Bollu ; Dong, Gang. / Baylis-Hillman chemistry : A one pot cross-coupling/allylboration reaction. In: Tetrahedron Letters. 2005 ; Vol. 46, No. 24. pp. 4209-4211.
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