Betamethasone and the human fetal ductus arteriosus

Nathan Wasserstrum, James C. Huhta, Giancarlo Mari, Dawood D. Sharif, Rita Willis, Nancy K. Neal

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

We used a sensitive Doppler echocardiographic technique to evaluate in utero the effects of betamethasone on the human ductus arteriosus. Transient, mild constriction of the ductus arteriosus 4–5 hours after the first injection of betamethasone occurred in two of 11 trials. The relatively mild and brief effects on the human ductus of betamethasone in usual doses are probably not clinically significant in most instances. Hence, they do not appear to contraindicate the use of glucocorticoids to promote fetal lung maturation.

Original languageEnglish (US)
Pages (from-to)897-900
Number of pages4
JournalObstetrics and Gynecology
Volume74
Issue number6
StatePublished - 1989
Externally publishedYes

Fingerprint

Ductus Arteriosus
Betamethasone
Constriction
Glucocorticoids
Lung
Injections

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

Wasserstrum, N., Huhta, J. C., Mari, G., Sharif, D. D., Willis, R., & Neal, N. K. (1989). Betamethasone and the human fetal ductus arteriosus. Obstetrics and Gynecology, 74(6), 897-900.

Betamethasone and the human fetal ductus arteriosus. / Wasserstrum, Nathan; Huhta, James C.; Mari, Giancarlo; Sharif, Dawood D.; Willis, Rita; Neal, Nancy K.

In: Obstetrics and Gynecology, Vol. 74, No. 6, 1989, p. 897-900.

Research output: Contribution to journalArticle

Wasserstrum, N, Huhta, JC, Mari, G, Sharif, DD, Willis, R & Neal, NK 1989, 'Betamethasone and the human fetal ductus arteriosus', Obstetrics and Gynecology, vol. 74, no. 6, pp. 897-900.
Wasserstrum N, Huhta JC, Mari G, Sharif DD, Willis R, Neal NK. Betamethasone and the human fetal ductus arteriosus. Obstetrics and Gynecology. 1989;74(6):897-900.
Wasserstrum, Nathan ; Huhta, James C. ; Mari, Giancarlo ; Sharif, Dawood D. ; Willis, Rita ; Neal, Nancy K. / Betamethasone and the human fetal ductus arteriosus. In: Obstetrics and Gynecology. 1989 ; Vol. 74, No. 6. pp. 897-900.
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