Binding of Escherichia coli RNA polymerase to a specific site located near the 3′-end of the avian sarcoma virus genome

Ramareddy Guntaka, Prasad Y. Rao, Richard A. Katz, S. Alex Mitsialis

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

We have isolated a unique 35 base pair region of avian tumor virus DNA that binds specifically to Escherichia coli RNA polymerase holoenzyme. Studies with various size classes of viral DNA coupled with restriction enzyme mapping data indicate that the binding site is located in the large terminal repeat of the viral genome and is within the first 50 nucleotides of the heteropolymeric region corresponding to the 3′-end of the virion RNA.

Original languageEnglish (US)
Pages (from-to)457-469
Number of pages13
JournalBBA Section Nucleic Acids And Protein Synthesis
Volume607
Issue number3
DOIs
StatePublished - May 30 1980
Externally publishedYes

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DNA Tumor Viruses
Avian Sarcoma Viruses
Restriction Mapping
Holoenzymes
Terminal Repeat Sequences
Viral Genome
Viral DNA
DNA-Directed RNA Polymerases
Base Pairing
Virion
Nucleotides
Binding Sites
Genome
RNA
Escherichia coli

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Binding of Escherichia coli RNA polymerase to a specific site located near the 3′-end of the avian sarcoma virus genome. / Guntaka, Ramareddy; Rao, Prasad Y.; Katz, Richard A.; Mitsialis, S. Alex.

In: BBA Section Nucleic Acids And Protein Synthesis, Vol. 607, No. 3, 30.05.1980, p. 457-469.

Research output: Contribution to journalArticle

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