Biological profile and response to anti-Pneumocystis agents of Pneumocystis carinii in cell culture

Linda Pifer, D. D. Pifer, D. R. Woods

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Although the growth characteristics of Pneumocystis carinii have been described in several cell culture systems, the response of this organism to the drugs of choice, trimethoprim-sulfamethoxazole and pentamidine isethionate, have not been described in vitro. The effect of various concentrations of drugs against P. carinii on the growth of this potentially hazardous opportunistic organism as well as the methodology for in vitro assay of these agents have been detailed. Fluorescence profiles illustrating size ranges of trophozoites and cysts derived from cell culture are described.

Original languageEnglish (US)
Pages (from-to)674-678
Number of pages5
JournalAntimicrobial Agents and Chemotherapy
Volume24
Issue number5
DOIs
StatePublished - Jan 1 1983

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Pneumocystis
Pneumocystis carinii
Cell Culture Techniques
Pentamidine
Trophozoites
Sulfamethoxazole Drug Combination Trimethoprim
Growth
Pharmaceutical Preparations
Cysts
Fluorescence
In Vitro Techniques

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

Cite this

Biological profile and response to anti-Pneumocystis agents of Pneumocystis carinii in cell culture. / Pifer, Linda; Pifer, D. D.; Woods, D. R.

In: Antimicrobial Agents and Chemotherapy, Vol. 24, No. 5, 01.01.1983, p. 674-678.

Research output: Contribution to journalArticle

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