Biology and pathogenesis of rhabdo- and filoviruses

Asit K. Pattnaik, Michael Whitt

Research output: Book/ReportBook

Abstract

Rhabdoviruses and Filoviruses are single-stranded, non-segmented, negative-strand RNA viruses, many of which cause significant morbidity and mortality in humans and animals. Certain members of these virus families have been used as excellent model systems to understand the molecular biology of replication, host responses to infections, and viral countermeasures. Rhabdoviruses have also been used as vaccine vectors as well as oncolytic agents. Studies on Filoviruses have now provided significant insights into how they enter susceptible cells, replicate and cause disease, and also how they evade the host’s immune mechanisms. This book addresses the most recent findings on Rhabdovirus and Filovirus structure, replication mechanisms, host cell responses to virus infections and viral countermeasures. Chapters on emerging viruses as well as approaches for therapeutic interventions have also been included. This book represents an authoritative text that brings together the most recent advances on the cellular and molecular biology of Rhabdo- and Filoviruses, including mechanisms of pathogenesis.

Original languageEnglish (US)
PublisherWorld Scientific Publishing Co.
Number of pages627
ISBN (Electronic)9789814635349
ISBN (Print)9789814635332
DOIs
StatePublished - Jan 1 2014

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Rhabdoviridae
Virus Diseases
Molecular Biology
Viruses
RNA Viruses
Cell Biology
Vaccines
Morbidity
Mortality
Therapeutics

All Science Journal Classification (ASJC) codes

  • Immunology and Microbiology(all)
  • Medicine(all)

Cite this

Biology and pathogenesis of rhabdo- and filoviruses. / Pattnaik, Asit K.; Whitt, Michael.

World Scientific Publishing Co., 2014. 627 p.

Research output: Book/ReportBook

Pattnaik AK, Whitt M. Biology and pathogenesis of rhabdo- and filoviruses. World Scientific Publishing Co., 2014. 627 p. https://doi.org/10.1142/P9394
Pattnaik, Asit K. ; Whitt, Michael. / Biology and pathogenesis of rhabdo- and filoviruses. World Scientific Publishing Co., 2014. 627 p.
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