Bone density in Ehlers-Danlos Syndrome

Laura Carbone, Frances Tylavsky, A. J. Bush, W. Koo, E. Orwoll, S. Cheng

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Ehlers-Danlos Syndrome (EDS) is the most common inherited disorder of connective tissue recognized. The objectives of the present study were to determine bone mineral density (BMD) and biochemical markers of bone metabolism in EDS. Twenty-three subjects with Type III EDS and 23 matched controls underwent BMD measurement by dual-Energy X-ray absorptiometry (DXA) of the lumbar spine and femoral neck. Health history questionnaires and biochemical markers of bone and connective tissue metabolism were also assessed. No significant differences in BMD at the lumbar spine or differences in biochemical markers of bone and connective tissue metabolism were found between EDS subjects and controls. EDS subjects had a significantly decreased BMD at the femoral neck compared with controls, but this difference disappeared after adjustment for body height, weight and physical activity levels.

Original languageEnglish (US)
Pages (from-to)388-392
Number of pages5
JournalOsteoporosis International
Volume11
Issue number5
DOIs
StatePublished - Jul 24 2000

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Ehlers-Danlos Syndrome
Bone Density
Connective Tissue
Biomarkers
Femur Neck
Bone and Bones
Spine
Body Height
Photon Absorptiometry
Body Weight
Health

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism

Cite this

Carbone, L., Tylavsky, F., Bush, A. J., Koo, W., Orwoll, E., & Cheng, S. (2000). Bone density in Ehlers-Danlos Syndrome. Osteoporosis International, 11(5), 388-392. https://doi.org/10.1007/s001980070104

Bone density in Ehlers-Danlos Syndrome. / Carbone, Laura; Tylavsky, Frances; Bush, A. J.; Koo, W.; Orwoll, E.; Cheng, S.

In: Osteoporosis International, Vol. 11, No. 5, 24.07.2000, p. 388-392.

Research output: Contribution to journalArticle

Carbone, L, Tylavsky, F, Bush, AJ, Koo, W, Orwoll, E & Cheng, S 2000, 'Bone density in Ehlers-Danlos Syndrome', Osteoporosis International, vol. 11, no. 5, pp. 388-392. https://doi.org/10.1007/s001980070104
Carbone L, Tylavsky F, Bush AJ, Koo W, Orwoll E, Cheng S. Bone density in Ehlers-Danlos Syndrome. Osteoporosis International. 2000 Jul 24;11(5):388-392. https://doi.org/10.1007/s001980070104
Carbone, Laura ; Tylavsky, Frances ; Bush, A. J. ; Koo, W. ; Orwoll, E. ; Cheng, S. / Bone density in Ehlers-Danlos Syndrome. In: Osteoporosis International. 2000 ; Vol. 11, No. 5. pp. 388-392.
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