Boron trifluoride induced fragmentation of β-Aryl-β-hydroxyketones

George Kabalka, David Tejedor, Nan Sheng Li, Malladi Reddy, Sarah Trotman

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

β-Aryl-β-hydroxy ketones are readily cleaved by boron trifluoride in non-protic solvents. The reaction appears to proceed via a non-synchronous Grobe fragmentation pathway.

Original languageEnglish (US)
Pages (from-to)8071-8072
Number of pages2
JournalTetrahedron Letters
Volume39
Issue number44
DOIs
StatePublished - Oct 29 1998
Externally publishedYes

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Ketones
boron trifluoride

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Boron trifluoride induced fragmentation of β-Aryl-β-hydroxyketones. / Kabalka, George; Tejedor, David; Li, Nan Sheng; Reddy, Malladi; Trotman, Sarah.

In: Tetrahedron Letters, Vol. 39, No. 44, 29.10.1998, p. 8071-8072.

Research output: Contribution to journalArticle

Kabalka, George ; Tejedor, David ; Li, Nan Sheng ; Reddy, Malladi ; Trotman, Sarah. / Boron trifluoride induced fragmentation of β-Aryl-β-hydroxyketones. In: Tetrahedron Letters. 1998 ; Vol. 39, No. 44. pp. 8071-8072.
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